78018-66-3

Upstream product

• 39659-25-1 3-Phenyl-2,4-dibenzoylpentane 
• 99408-66-9 3,5-diphenyl-4-aza-2,4-heptadiene 
• 538-51-2 benzylidene phenylamine 
• 100-52-7 benzaldehyde 
• 7664-41-7 ammonia 
• 64-17-5 ethanol 
• 93-55-0 1-phenyl-propan-1-one 
• 108-88-3 toluene 
• 133145-92-3 1-phenylpropan-1-one O-acetyl oxime 
• 4258-37-1 1,3-diphenyl-2-methylpropene-3-one 
• 78018-65-2 3,5-dimethyl-2,4,6-triphenyl pyrylium tetrafluoroborate 
• 19111-96-7 2,4,6-Triphenyl-3,5-dimethylpiperidinol-4 

Relevant academic research and scientific papers

Synthesis of Highly Substituted Pyridines through Copper-Catalyzed Condensation of Oximes and α,β-Unsaturated Imines

A copper-catalyzed condensation reaction of oxime acetates and α,β-unsaturated ketimines to give pyridine derivatives is reported. The reaction features mild conditions, high functional-group compatibility, and high regioselectivity with respect to unsymmetrical oxime acetates, thus allowing the preparation of a wide range of polysubstituted pyridines, many of which are not readily accessible by conventional condensation methods.

One-Pot Synthesis of Benzene and Pyridine Derivatives via Copper-Catalyzed Coupling Reactions

A highly efficient one-pot synthesis of polysubstituted pyridine has been achieved through copper-catalyzed oxidative sp3 C?H coupling of acetophenones with toluene derivatives. Besides, the polysubstituted benzene was obtained through copper-catalyzed coupling of acetophenones. Both of the reactions exhibited a good functional group tolerance to produce a 2,4,6-triphenylpyridine or 1,3,5-triarylbenzene in high yields. Compared with previous methods, these transformations allow a highly flexible and efficient preparation of substituted pyridines and benzenes. (Figure presented.).

Ceric ammonium nitrate (CAN) catalyzed one-pot synthesis of fully substituted new indeno[1,2-b]pyridines at room temperature by a multi-component reaction

Ceric ammonium nitrate (CAN) (10 mol%) in ethanol has been found to be an efficient catalyst for the one-pot multi-component synthesis of fully substituted new indeno[1,2-b]pyridines through a combination of 1,3-indandione, propiophenone or 2-phenylacetop

Kinetics and Mechanisms of Nucleophilic Displacements with Heterocycles as Leaving Groups. 2. N-Benzylpyridinium Cations: Rate Variation with Steric Effects in the Leaving Group

N-Benzyl groups are transferred to piperidine from pyridinium ions by unimolecular SN1 and/or bimolecular SN2 mechanisms.Steric acceleration by α-phenyl groups is reduced by an adjacent β-methyl group but increased by constraining th

Boron Trifluoride as a Cyclodehydrating Agent: Synthesis of Nitrogen Heterocycles via Pyrylium Tetrafluoroborates

Pyrylium cations (1-12,Z = O+) have been prepared in high yields by the interaction of chalkones (in slight excess) and different ketones using BF3-etherate as cyclodehydrating agent or from 1,5-diketones in the presence of HBr and chalkone as hydrogen abstractor.The pyrylium cations have been converted into the corresponding nitrogen heterocycles (1-12;Z=N).