78277-26-6

Basic information

• Product Name: Hexanoic acid, 6-bromo-, phenylmethyl ester
• CAS NO: 78277-26-6
• Molecular Formula: C13H17BrO2
• Molecular Weight: 285.181
• Mol File: 78277-26-6.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: Hexanoic acid, 6-bromo-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanoic acid, 6-bromo-, phenylmethyl ester(78277-26-6)
• EPA Substance Registry System: Hexanoic acid, 6-bromo-, phenylmethyl ester(78277-26-6)

Safety Data

• Hazardous Substances Data: 78277-26-6(Hazardous Substances Data)

Upstream product

• 125878-06-0 6-hydroxyhexanoic acid phenylmethyl ester 
• 4224-70-8 6-bromohexanoic acid 
• 7285-83-8 2,4,6-tris(benzyloxy)-1,3,5-triazine 
• 57978-00-4 6-bromohexanal 
• 1334402-02-6 C₆H₁₀BrFO 
• 100-51-6 benzyl alcohol 
• 104-15-4 toluene-4-sulfonic acid 
• 7757-82-6 sodium sulfate 
• 100-39-0 benzyl bromide 
• 501-53-1 benzyl chloroformate 
• 22809-37-6 6-bromohexanoyl chloride 

Downstream Products

• 93415-09-9 6-iodo-hexanoic acid benzyl ester 
• 1356258-14-4 C₂₅H₂₆O₄ 
• 1356258-17-7 C₃₁H₃₆O₆ 
• 173443-26-0 (1R,2R,3S,5S)-3-Benzoyloxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid 5-benzyloxycarbonyl-pentyl ester 

Relevant articles and documents

LIPID NANOPARTICLE COMPOSITION

Provided herein are lipids that can be used in combination with other lipid components, such as neutral lipids, cholesterol and polymer conjugated lipids, to form lipid nanoparticles for delivery of therapeutic agents (e.g., nucleic acid molecules) for therapeutic or prophylactic purposes, including vaccination.

MOLECULES THAT STIMULATE THE IMMUNE SYSTEM FOR TREATMENT OF DRUG ADDICTION, METHODS OF SYNTHESIS, ANTIDRUG VACCINE AND USES

This technology relates to immune system stimulating molecules to be used in the treatment of drug addiction and abuse and their synthesis processes. These molecules have a calixarene chemical structure, preferably calix[4]arene and/or calix[8]arene, coupled to an hapten analogous to cocaine, preferably GNE and/or GNC. An anti-drug vaccine, specifically anti-cocaine, is also described using such molecules. The anti-drug vaccine can be also used to prevent fetal exposure to drugs in pregnant women who use drugs and do not wish or cannot stop their use during pregnancy.

CATIONIC LIPID

The present invention provides a cationic lipid which is able to be used for nucleic acid delivery to the cytoplasm. A cationic lipid according to the present invention is, for example, a compound represented by formula (1a) or a pharmaceutically acceptable salt thereof. (In formula (1a), each of L1 and L2 independently represent an alkylene group having 3-10 carbon atoms; each of R1 and R2 independently represent an alkyl group having 4-22 carbon atoms or an alkenyl group having 4-22 carbon atoms; X1 represents a single bond or -CO-O-; and ring P represents one of formulae (P-1) to (P-5).)(In formulae (P-1) to (P-5), R3 represents an alkyl group having 1-3 carbon atoms.)