78443-79-5

Usage

Uses

Used in Pharmaceutical Research:
(E)-7-(2-(benzyloxy)-4,6-dichlorophenyl)-3,5-dihydroxyhept-6-enoic acid is used as a potential candidate for pharmaceutical applications due to its complex structure and the presence of functional groups that may exhibit biological activity. (E)-7-(2-(benzyloxy)-4,6-dichlorophenyl)-3,5-dihydroxyhept-6-enoic acid's specific properties and potential applications would need to be further investigated through in-depth studies and analysis.
Used in Agrochemical Research:
In the agrochemical industry, (E)-7-(2-(benzyloxy)-4,6-dichlorophenyl)-3,5-dihydroxyhept-6-enoic acid is used as a compound of interest for potential development into agrochemical products. Its unique structure and functional groups may offer new avenues for pest control, crop protection, or other agricultural applications, pending further research and development.

Upstream product

• 78443-77-3 methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-5-hydroxy-3-oxo-6-heptenoate 
• 78443-74-0 (E)-3-<2,4-dichloro-6-(phenylmethoxy)phenyl>-2-propenal 
• 78443-73-9 2,4-dichloro-6-(phenylmethoxy)benzaldehyde 
• 78443-72-8 4,6-dichlorosalicylaldehyde 
• 100-39-0 benzyl bromide 
• 78443-78-4 methyl (E)-7-<2,4-dichloro-6-(phenylmethoxy)phenyl>-3,5-dihydroxy-6-heptenoate 

Downstream Products

• 78444-23-2 (+)-trans-(E)-6-<2-<2,4-dichloro-6-(phenylmethoxy)phenyl>ethyl>-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one 
• 78443-80-8 (E)-6-<2-<2,4-dichloro-6-(phenylmethoxy)phenyl>ethenyl>-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one 
• 78443-80-8 (E)-6-<2-<2,4-dichloro-6-(phenylmethoxy)phenyl>ethenyl>-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one 

Relevant academic research and scientific papers

Substituted pyranone inhibitors of cholesterol synthesis

The methyl, ethyl, n-propy, 2-(acetylamino)ethyl, or 1-(2,3-dihydroxy)propyl ester of E-(3R,5S)-7-(4'-fluoro-3,3',5-trimethyl[1,1'-biphenyl]-2-yl)-3,5-dihydroxy-6-heptenoic acid of structural formula: STR1 are HMG-CoA reductase inhibitors useful in the treatment of conditions associated with hypercholesterolemia.

Substituted pyranone inhibitors of cholesterol synthesis

6-Phenyl-, phenylalkyl- and phenylethenyl-4-hydroxytetrahydropyran-2-ones in the 4(R)-trans stereoisomeric forms are potent inhibitors of cholesterol synthesis by virtue of their ability to inhibit the enzyme, 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

SUBSTITUTED PYRANONE INHIBITORS OF CHOLESTEROL SYNTHESIS

6-Phenyl-, phenylalkyl-and phenylethenyl-4-hydroxytetrahydropyran-2-ones in the 4(R)-trans stereoisomeric forms are potent inhibitors of cholesterol synthesis by virtue of their ability to inhibit the enzyme, 3-hydroxy-3-methylglutaryl-coenzyme A reductas

Cis/trans isomerization of 6-(substituted-aryl-ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones

Biologically inactive cis-6-(substituted-arylethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones are isomerized to the corresponding anti-hypercholesterolemic trans-isomers by heating in the presence of a heavy metal salt.