786668-40-4

Upstream product

• 111-29-5 1 ,5-pentanediol 
• 99016-97-4 (Z)-7-(benzyloxy)hept-2-en-1-ol 
• 786668-19-7 methyl (Z)-7-(benzyloxy)hept-2-enoate 
• 99016-98-5 (2R,3S)-3-[4-(benzyloxy)butyl]oxiran-2-ylmethanol 
• 100-39-0 benzyl bromide 
• 4541-15-5 5-(benzyloxy)-1-pentanol 
• 78999-24-3 5-benzyloxy-1-pentanal 
• 858666-74-7 (2'R,3'S,4R,5S)-(+)-3-(7'-benzyloxy-3'-hydroxy-2'-methylheptanoyl)-4-methyl-5-phenyloxazolidin-2-one 

Downstream Products

• 858666-78-1 (2S,3S)-(+)-7-benzyloxy-1-tert-butyldiphenylsilyloxy-3-tert-butyldimethylsilyloxy-2-methylheptane 
• 786668-31-3 {(S)-2-[(2S,6R)-6-But-3-enyl-6-(4-methoxy-benzyloxy)-tetrahydro-pyran-2-yl]-propoxy}-tert-butyl-diphenyl-silane 
• 786668-29-9 (9S,10S)-11-(tert-Butyl-diphenyl-silanyloxy)-9-hydroxy-10-methyl-undec-1-en-5-one 
• 786668-27-7 (S)-6-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-tetrahydro-pyran-2-one 
• 887001-91-4 (2S,5S,7S,1'S,2'S,1''S)-(+)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-2-(1',2'-epoxy-3'-iodo-2'-methylprop-1'-yl)-1,6-dioxaspiro[4.5]decane 
• 858666-83-8 4-benzenesulfonyl-1-benzyloxy-2,9-bis-(tert-butyl-dimethyl-silanyloxy)-11-(tert-butyl-diphenyl-silanyloxy)-10-methyl-undecan-5-one 
• 858666-81-6 4-benzenesulfonyl-1-benzyloxy-2,9-bis-(tert-butyl-dimethyl-silanyloxy)-11-(tert-butyl-diphenyl-silanyloxy)-10-methyl-undecan-5-ol 
• 858666-85-0 (2S,9S,10S)-(-)-1-benzyloxy-2,9-bis-(tert-butyldimethylsilyloxy)-11-(tert-butyldiphenylsilyloxy)-10-methylundecane-5-one 
• 858666-63-4 (1'E,2S,5R,7S,1''S)-(+)-2-(6'-benzyloxy-2'-methyl-1'-hexen-4'-yn-1'-yl)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-1,6-dioxaspiro[4.5]decane 
• 858666-95-2 tert-Butyl-{(S)-2-[(2S,5R,7S)-2-((E)-3-iodo-2-methyl-propenyl)-1,6-dioxa-spiro[4.5]dec-7-yl]-propoxy}-diphenyl-silane 
• 887001-88-9 (5S,6S)-(+)-5-tert-butyldimethylsilyloxy-7-tert-butyldiphenylsilyloxy-6-methylheptan-1-ol 
• 858666-69-0 (5S,6S)-(+)-5-tert-butyldimethylsilyloxy-7-tert-butyldiphenylsilyloxy-6-methylheptan-1-al 
• 858666-91-8 (1'E,2S,5R,7S,1''S)-(+)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-2-(2'-ethoxycarbonyl-2'-methyl-1'-propenyl)-1,6-dioxaspiro[4.5]decane 
• 887001-90-3 (2S,5S,7S,1'S,2'S,1''S)-(+)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-2-(1',2'-epoxy-3'-hydroxy-2'-methylprop-1'-yl)-1,6-dioxaspiro[4.5]decane 

Relevant academic research and scientific papers

Synthesis of the ABC tricyclic fragment of the pectenotoxins via stereocontrolled cyclization of a γ-hydroxyepoxide appended to the AB spiroacetal unit

The stereocontrolled synthesis of the C1-C16 ABC spiroacetal-containing tricyclic fragment of pectenotoxin-7 6 has been accomplished. The key AB spiroacetal aldehyde 9 was successfully synthesized via acid catalyzed cyclization of protected ketone precurs

Synthesis of the ABC fragment of the pectenotoxins

(Chemical Equation Presented) A highly stereocontrolled synthesis of the C1-C16 ABC spiroacetal-containing fragment 5 of PTX7 (4) has been achieved. Appendage of the C ring to the AB fragment involved Wittig reaction of spiroacetal aldehyde 8 with a stabi

Access to both anomers of pectenotoxin spiroketals by kinetic spiroketalization

A concise synthesis of both AB ring spiroisomers of the pectenotoxins is described. The nonanomeric AB spiroketal ring system of the pectenotoxins-1, -2, -3, and -6 is formed under very mild, kinetic spiroketalization conditions, along with the anomeric i