78693-66-0

Usage

Uses

Used in Electronics Industry:
(2,2,3,3,3-Pentafluoropropyl)benzene is used as a solvent for various applications in the electronics industry, such as cleaning and degreasing of electronic components. Its high chemical stability and resistance to heat make it suitable for use in this industry.
Used in Pharmaceutical Industry:
(2,2,3,3,3-Pentafluoropropyl)benzene is used as a solvent in the pharmaceutical industry for the synthesis of various drugs and pharmaceutical compounds. Its properties allow for efficient reactions and the production of high-quality pharmaceutical products.
Used in Agrochemicals Industry:
(2,2,3,3,3-Pentafluoropropyl)benzene is used as a solvent in the agrochemicals industry for the production of various agrochemical products, such as pesticides and herbicides. Its versatility and stability make it a valuable compound in this industry.
Used as a Precursor in Chemical Production:
(2,2,3,3,3-Pentafluoropropyl)benzene is also used as a precursor in the production of specialty chemicals and polymers. Its unique properties allow for the creation of a wide range of chemical products, further demonstrating its importance in the chemical industry.

Upstream product

• 75-61-6 dibromodifluoromethane 
• 100-39-0 benzyl bromide 
• 124898-13-1 trimethyl(pentafluoroethyl)silane 
• 100-44-7 benzyl chloride 
• 100-51-6 benzyl alcohol 
• 60007-39-8 pentafluoroethylcopper(I) 
• 394-52-5 pentafluoroethyl phenyl ketone 
• 345-40-4 2,2,3,3,3-Pentafluoro-1-phenyl-propan-1-ol 
• 78693-68-2 Toluene-4-sulfonic acid 2,2,3,3,3-pentafluoro-1-phenyl-propyl ester 
• 1514-87-0 metyhyl chlorodifluoroacetate 

Relevant academic research and scientific papers

Pentafluoroethylating compositions

The present invention relates to pentafluoroethylating compositions, processes for obtaining them, and their use in pentafluoroethylation reactions.

PENTAFLUOROETHYLATING COMPOSITIONS

The present invention relates to pentafluoroethylating compositions, processes for obtaining them, and their use in pentafluoroethylation reactions.

Cupration of C2F5H: Isolation, structure, and synthetic applications of [K(DMF)2][(t -BuO)Cu(C2F 5)]. Highly efficient pentafluoroethylation of unactivated aryl bromides

Pentafluoroethane, C2F5H (HFC-125), is smoothly cuprated with preisolated or in situ-generated [K(DMF)][(t-BuO)2Cu] to give [K(DMF)2][(t-BuO)Cu(C2F5)] (1) in nearly quantitative yield. Complex 1 has been isolated, structurally characterized, and demonstrated to be an exceedingly versatile pentafluoroethylating reagent for a variety of substrates, including unactivated aryl bromides.

Synthesis of functionalized long-chain perfluoroalkanes from methyl halodifluoroacetates: a process of difluorocarbene insertion into copper-carbon bonds

Treatment of XCF2CO2Me (X = Cl, Br) with organic halides in the presence of KF and catalytic amounts of CuI at 80-120 deg C for 3-8 h in DMF gave long-chain perfluoroalkylated compounds which are considered to be former by the insertions of CF2(..) into carbon-copper bonds.

The reactions of copper-dibromodifluoromethane-amide systems with alcohols

1,1,1-Trifluoro-2-arylethanes can be prepared by the trifluoromethyldehydroxylation of benzyl alcohols using the copper-dibromodifluoromethane-amide reaction system, although the yields are low.The mechanism of the reaction may involve chelation of the substrate to copper so that α-substituted benzyl alcohols and other alcohols are unreactive.

A NOVEL AND CONVENIENT METHOD FOR TRIFLUOROMETHYLATION OF ORGANIC HALIDES USING CF3SiR'3/KF/Cu(I) SYSTEM

Fluoride ion induced cross-coupling reaction of organic halides with trifluoromethyltrialkylsilanes takes place in the presence of Cu(I) salts under mild reaction conditions to give the corresponding trifluoromethylated products in high yields.

Proton-Transfer Reactions. 2. Effects of Internal Return on Reactivity Difference between Alkoxide-Promoted Eliminations in tert-Butyl alcohol and Ethyl Alcohol

Kinetics of alkoxide-promoted dehydrofluorination reactions are reported for the series C6H5CH2CH2F (I), C6H5CH2CHF2 (II), C6H5CH2CF3 (III), and C6H5CH2CF2CF3 (V).Rates and activation parameters 3 (M-1 s-1)(50 deg C), ΔH* (kcal mol-1), and ΔS*, (eu)> are respectively: (a) using potassium tert-butoxide in tert-butyl alcohol, I (1.88 * 10-4, 19.1, -16.8), II (1.18 * 10-3, 20.3, -9.3), III (2.15 * 10-3, 22.1, -2.4), V (3.93 * 10-2, 16.9, -12.7); and (b) using sodium ethoxide in ethanol, I (1.32 * 10-6, 25.6, -6.5), II (5.28 * 10-7, 29.7, 3.0), III (3.45 * 10-7, 32.6, 12.5), V (5.41 * 10-5, 27.7, 7.6).The variation in tert-butoxide:ethoxide ratios of 140 (I), 2200 (II), 6200 (III), and 730 (V) are discussed in terms of a two-step mechanism with varying amounts of internal return for II, III, and V.Differences in reactivity for groups attached to the benzylic carbon (-CF3, -CF2Cl, -CHF2, -CF2CF3) and variation of ΔS* values for these reactions are also discussed in terms of a two-step mechanism.