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Methyl 2-chloro-5-methylisonicotinate is a chemical compound with the molecular formula C8H8ClNO2. It is a derivative of isonicotinic acid and is known for its versatile reactivity. Methyl 2-chloro-5-Methylisonicotinate is commonly used in the synthesis of pharmaceuticals and agrochemicals and is a promising building block in the production of various organic compounds, particularly in the field of medicinal chemistry for the development of new drugs with potential therapeutic applications.

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  • 787596-43-4 Structure
  • Basic information

    1. Product Name: Methyl 2-chloro-5-Methylisonicotinate
    2. Synonyms: Methyl 2-chloro-5-Methylisonicotinate
    3. CAS NO:787596-43-4
    4. Molecular Formula: C8H8ClNO2
    5. Molecular Weight: 185.60762
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 787596-43-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Methyl 2-chloro-5-Methylisonicotinate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Methyl 2-chloro-5-Methylisonicotinate(787596-43-4)
    11. EPA Substance Registry System: Methyl 2-chloro-5-Methylisonicotinate(787596-43-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 787596-43-4(Hazardous Substances Data)

787596-43-4 Usage

Uses

Used in Pharmaceutical Industry:
Methyl 2-chloro-5-methylisonicotinate is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
Methyl 2-chloro-5-methylisonicotinate is used as a building block in the production of agrochemicals, contributing to the creation of compounds that can be utilized in agricultural applications.
It is important to handle Methyl 2-chloro-5-methylisonicotinate with caution and follow proper safety protocols, as it can be hazardous if not handled properly.

Check Digit Verification of cas no

The CAS Registry Mumber 787596-43-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,7,5,9 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 787596-43:
(8*7)+(7*8)+(6*7)+(5*5)+(4*9)+(3*6)+(2*4)+(1*3)=244
244 % 10 = 4
So 787596-43-4 is a valid CAS Registry Number.

787596-43-4Downstream Products

787596-43-4Relevant articles and documents

Substituted tricyclic compound serving as PRMT5 inhibitor and application of substituted tricyclic compound

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, (2021/04/14)

The invention belongs to the field of medical chemistry, relates to a substituted tricyclic compound serving as a PRMT5 inhibitor and application of the substituted tricyclic compound, and particularly provides a compound shown as a formula (A) or an isom

INHIBITORS OF KEAP1-Nrf2 PROTEIN-PROTEIN INTERACTION

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, (2020/03/01)

Sultam compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with the KEAP1-Nrf2 interaction, such as inflammatory bowel disease, including Crohn's disease and ulcerative colitis.

PROCESS FOR PREPARING 1-ARYLSULFONYL-PYRROLIDINE-2-CARBOXAMIDE TRANSIENT RECEPTOR POTENTIAL CHANNEL ANTAGONIST COMPOUNDS AND CRYSTALLINE FORMS THEREOF

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Paragraph 0429; 0433-0438, (2019/09/12)

The invention relates generally to methods of preparing 1-arylsulfonyl-pyrrolidine-2-carboxamide Transient Receptor Potential channel antagonist compounds of the following structure (I): (I) The invention further relates to solvate and co-crystal polymorphs of crystalline formula (I), and methods of preparation thereof.

PRMT5 INHIBITORS

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, (2019/05/30)

The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts thereof, which are PRMT5 inhibitors.

APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS AND METHODS OF USE THEREOF

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Page/Page column 57, (2018/12/13)

The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts and esters thereof: which inhibit the Apoptosis signal-regulating kinase 1 (ASK-1), which associated with autoimmune disorders, neurodegenerative disorders, inflammatory diseases, chronic kidney disease, cardiovascular disease. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from ASK-1 related disease. The invention also relates to methods of treating an ASK-1 related disease in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The present invention specifically relates to methods of treating ASK-1 associated with hepatic steatosis, including non-alcoholic fatty liver disease (NAFLD) and non-alcohol steatohepatitis disease (NASH).

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND

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Paragraph 0291, (2017/08/01)

The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as a medicament such as a prophylactic or therapeutic drug for Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies and the like, and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof. wherein each symbol is as described in the attached DESCRIPTION.

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