790-82-9

Basic information

• Product Name: 4,4'-DIACETYLDIPHENYLMETHANE
• Synonyms: 1-[4-(4-Acetylbenzyl)phenyl]ethanone;4,4'-DIACETYLDIPHENYLMETHANE;BIS(4-ACETYLPHENYL)METHANE;BIS(P-ACETYL)DIPHENYLMETHANE;4,4''-DIACETYLDIPHENYLMETHANE 98%;4,4'-METHYLENEBIS(ACETOPHENONE)
• CAS NO: 790-82-9
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.31
• Mol File: 790-82-9.mol

Chemical Properties

• Melting Point: 93°C
• Boiling Point: 240-245 °C(Press: 6 Torr)
• Appearance: /
• Density: 1.088±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4,4'-DIACETYLDIPHENYLMETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DIACETYLDIPHENYLMETHANE(790-82-9)
• EPA Substance Registry System: 4,4'-DIACETYLDIPHENYLMETHANE(790-82-9)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 790-82-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4,4'-Diacetyldiphenylmethane is used as an intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the production of complex organic compounds.
Used in Rubber and Plastics Industry:
In the rubber and plastics industry, 4,4'-Diacetyldiphenylmethane is used as a precursor in the manufacturing process to enhance the properties of these materials.
Used in Coatings and Inks Industry:
4,4'-Diacetyldiphenylmethane is used as a powerful photoinitiator for the curing of various coatings and inks, improving their performance and durability.
Used in Organic Synthesis:
As a reagent in organic synthesis, 4,4'-Diacetyldiphenylmethane is used for the preparation of a wide array of organic compounds, contributing to the advancement of chemical research and product development.
Used in Medicinal Research:
4,4'-Diacetyldiphenylmethane is studied for its potential medicinal properties, such as antioxidant and anti-inflammatory effects, serving as a candidate for the development of new therapeutic agents.

Upstream product

• 7446-70-0 aluminium trichloride 
• 101-81-5 Diphenylmethane 
• 75-36-5 acetyl chloride 
• 110-91-8 morpholine 
• 99-91-2 para-chloroacetophenone 
• 32825-32-4 diphenylmethane tricarbonylchromium 
• 13329-40-3 4-Iodoacetophenone 
• 369386-31-2 4-[(2-pyridyldimethylsilyl)methyl]acetophenone 

Downstream Products

• 790-83-0 4,4'-methylenedibenzoic acid 
• 13007-03-9 bis-(4-isopropenyl-phenyl)-methane 
• 964-68-1 4,4'-benzophenonedicarboxylic acid 
• 4072-68-8 bis-(4-bromoacetyl-phenyl)-methane 
• 79541-71-2 bis[4-(1-hydroxyethyl)phenyl]methane 
• 20176-56-1 bis-[4-(1-hydroxyimino-ethyl)-phenyl]-methane 
• 861531-58-0 3,3'-dinitro-4,4'-methanediyl-di-benzoic acid 
• 76947-19-8 4,4'-diacetyl-2,2'-dinitrodiphenylmethane 
• 94374-83-1 Bis-(4-dichloracetylphenyl)-methan 
• 28179-20-6 4,4'-Bis-dibromacetyl-diphenylmethan 
• 4780-53-4 1,1',1'',1'''-(ethene-1,1,2,2-tetrayltetrakis(benzene-4,1-diyl))tetrakis(ethan-1-one) 
• 46835-41-0 bis(4-vinylphenyl)methane 
• 21192-56-3 bis(4-ethylphenyl)methanone 
• 147613-78-3 bis(4-ethynylphenyl)methanone 

Relevant articles and documents

A Cu(ii) metallocycle for the reversible self-assembly of coordination-driven polyrotaxane-like architectures

We report the design and synthesis of a Cu(ii) metallocycle (1) and use the possibility to expand the Cu(ii) coordination sphere to self-assemble mechanically interlocked species via interpenetration. Metallocycle 1 can be used as a platform to reversibly

Divinyl aromatic compounds and Di(methacrylates) prepared by acid-catalyzed transformations of bis[4-(1-hydroxyethyl)phenyl]alkanes

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(graph presented) Pharmacologically important diarylmethane structures have been prepared in a straightforward manner through sequentially integrated Pd-catalyzed cross-coupling reactions. (2-Pyridyl)silylmethylstannane was found to be an air-stable, storable, and versatile coupling platform in this synthetic strategy.

Aqueous hydroxide as a base for palladium-catalyzed amination of aryl chlorides and bromides

The amination of aryl halides in the presence of inexpensive and air-stable alkali metal hydroxide bases and Pd[P(t-Bu)3]2 as catalyst gave arylamines in high yields. The reactions were conducted with a catalytic amount of cetyltrimethylammonium bromide as phase-transfer agent and either aqueous hydroxide or solid hydroxide in the presence of water. This combination of alkali metal hydroxide base, H2O, and the ammonium salt performed as well as NaO-t-Bu in the amination of p-chlorotoluene with dibutylamine. Hydroxide base was suitable for reactions of a wide range of aryl chlorides and bromides with aliphatic and aromatic amines. Some functional groups that were intolerant of tert-butoxide base, such as esters, enolizable ketones, nitriles, and nitro groups, were tolerated by the combination of hydroxide base, H2O, and cetyltrimethylammonium bromide in toluene solvent.

Extended scope of in situ iodotrimethylsilane mediated selective reduction of benzylic alcohols

Iodotrimethylsilane, generated in situ from chlorotrimethylsilane and sodium iodide in acetonitrile, selectively reduces moderately electron deficient benzylic alcohols to the analogous toluenes; other reduction sensitive functional groups such as ketone, aldehyde, nitrile, and nitro are unaffected.

A Convenient Synthesis of MacrocyclicParacyclophanes

The paracyclophanedienes 9-11 were prepared in good yields by a McMurry cyclization of the bis(4-acylphenyl)methanes 5 and 6 and of bis(4-acetylphenyl) ether (7), respectively. - Key Words: Cyclophanes / Coupling reaction / McMurry reaction

The 'Inverse Electron-demand' Diels-Ader Reaction in Polymer Synthesis. Part 1. A Convenient Synthetic Route to Diethynyl Aromatic Compounds

The simple procedure whereby acetophenone derivatives are converted, by reaction with phosphoryl chloride and N,N-dimethylformamide, into β-chlorocinnamaldehydes, and thence, by base-induced elimination, into ethynylarenes, has been extended to diketones of the type MeCOC6H4COMe (m- and p-) and (p-MeCOC6H4)2X (X = O, S, SO2, CH2, CO, or a single bond): the corresponding diethynyl compounds are obtained by this route in acceptable yield. 1,3,5-Triacetylbenzene is similarly converted into 1,3,5-triethynylbenzene.

Electrophilic Substitution in (Arene)tricarbonylchromium Complexes. Part 1.

The Friedel-Crafts acetylation of several (arene)tricarbonylchromium complexes have been investigated.From the results it is concluded that the tricarbonylchromium group deactivates to a small extent towards electrophilic substitution the ring to which it is attached.In the case of tricarbonyl(diphenylmethane)chromium (1; n=1), however, attack occurred on both rings to about an equal extent, possible explanations for this unexpected behaviour are advanced.