79144-43-7

Upstream product

• 140-29-4 phenylacetonitrile 
• 104-55-2 3-phenyl-propenal 
• 14371-10-9 (E)-3-phenylpropenal 
• 100-42-5 styrene 
• 201230-82-2 carbon monoxide 
• 7677-24-9 trimethylsilyl cyanide 
• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 

Downstream Products

• 6443-81-8 2,5-diphenylpentanonitrile 

Relevant academic research and scientific papers

Practical Synthesis of (Z)-α,β-Unsaturated Nitriles via a One-Pot Sequential Hydroformylation/Knoevenagel Reaction

Herein, the synthesis of (Z)-α,β-unsaturated nitriles by a sequential hydroformylation/Knoevenagel reaction has been first developed. A variety of crude α-olefins from Fischer-Tropsch synthesis, internal and special olefins, as well as alkynes could be transformed into value-added alkenyl nitriles (39 examples) up to 90% yield. Remarkably, compared with commonly used tedious multistep reactions, the one-pot protocol features cheap and easily available raw materials, excellent chemo-, regio-, and stereoselectivity, very mild reaction conditions, and easy scale-up production.

Metal-Free Direct C?H Cyanation of Alkenes

A metal-free and direct alkene C?H cyanation is described. Directing groups are not required and the mechanism involves electrophilic activation of the alkene by a cyano iodine(III) species generated in situ from a [bis(trifluoroacetoxy)iodo]arene and tri

Manganese Catalyzed α-Olefination of Nitriles by Primary Alcohols

Catalytic α-olefination of nitriles using primary alcohols, via dehydrogenative coupling of alcohols with nitriles, is presented. The reaction is catalyzed by a pincer complex of an earth-abundant metal (manganese), in the absence of any additives, base, or hydrogen acceptor, liberating dihydrogen and water as the only byproducts.

Facile Preparation of α-Cyano-α,ω-Diaryloligovinylenes: A New Class of Color-Tunable Solid Emitters

An efficient Knoevenagel condensation reaction was used to construct a series of α-cyano-α,ω-diaryloligovinylenes, which show prominent fluorescence emission in the solid state. On investigating the effect of conjugation length on fluorescent properties,

Structural and computational studies of 2,5-diarylpenta-2,4-dienenitriles

2,5-Diarylpenta-2,4-dienenitriles 1-9 were synthesized and characterized by the high resolution 1H, 13C, 1H-1H COSY and 1H-13C COSY spectra. Spectral data indicate the trans arrangement of

Reconstructed hydrotalcite as a highly active heterogeneous base catalyst for carbon-carbon bond formations in the presence of water

The aldol reaction of carbonyl compounds is efficiently catalyzed by reconstructed hydrotalcites, obtained by treating the Mg-Al mixed oxide with water, as solid base catalysts in the presence of water. The catalysis of the reconstructed hydrotalcites is attributable to the surface base sites, created during the organization of the layered structure, with uniformly distributed strength. Furthermore, the reconstructed hydrotalcites provide a unique acid-base bifunctional surface capable of promoting the Knoevenagel and Michael reactions of nitriles with carbonyl compounds.

REACTIONS OF TITANIUM DERIVATIVES OF CERTAIN CH ACIDS WITH CARBONYL COMPOUNDS. II. ALDOL CONDENSATIONS WITH TITANIUM DERIVATIVES OF BENZYL CYANIDE, ISOPROPYL PHENYLACETATE, AND PHENYL BENZYL AND ETHYL BENZYL KETONES

The titanium derivatives of benzyl cyanide, isopropyl phenylacetate, and phenyl benzyl and ethyl benzyl ketones, unlike the corresponding alkali-metal salts, react with aldehydes and ketones in THF at -78 to 20 deg C to form high yields of the products fr