79149-55-6Relevant academic research and scientific papers
Direct defluorinative amidation-hydrolysis reaction of gem-difluoroalkenes with N,N-dimethylformamide, and primary and secondary amines
Wang, Biyun,Zhao, Xianghu,Liu, Qingyun,Cao, Song
, p. 8546 - 8552 (2018/12/01)
A novel and efficient method for the synthesis of arylacetamides by the reactions of gem-difluoroalkenes with N,N-dialkylformamides, and primary and secondary amines with the assistance of KOtBu and water was developed.
Palladium-catalyzed intermolecular α-arylation of zinc amide enolates under mild conditions
Hama, Takuo,Culkin, Darcy A.,Hartwig, John F.
, p. 4976 - 4985 (2007/10/03)
The intermolecular α-arylation and vinylation of amides by palladium-catalyzed coupling of aryl bromides and vinyl bromides with zinc enolates of amides is reported. Reactions of three different types of zinc enolates have been developed. The reactions of
Synthesis of N,N-dimethyl α-aryl and α,α-diarylacetamides by radical nucleophilic substitution reactions
Palacios, S. M.,Asis, S. E.,Rossi, R. A.
, p. 111 - 116 (2007/10/02)
A family of N,N-dimethyl, α-aryl and α,α-diaryl acetamides was synthesized by reaction of aryl halides with N,N-dimethyl acetamide enolate ions in liquid ammonia.The reactions followed the SRN1 mechanism for nucleophilic substitution.They were initiated by light (350 nm), when the aryl halides or aryl halides bearing electron-donating groups were the substrate, and by potassium metal dissolved in liquid ammonia when the substituents on the aryl halides were electron-withdrawing groups. Key Words: SRN1 / nucleophilic substitution / synthesis / acetamide compounds / herbicides
