79636-93-4

Upstream product

• 2362-12-1 4-Bromo-2-methylphenol 
• 75-03-6 ethyl iodide 

Downstream Products

• 79636-94-5 5-bromo-2-ethoxybenzaldehyde 
• 1180015-53-5 C₁₇H₁₉BrO₂ 
• 7062-41-1 2-(5-bromo-2-ethoxyphenyl)acetonitrile 
• 1094438-61-5 4-bromo-2-(bromomethyl)-1-ethoxybenzene 
• 1314711-29-9 1-(5-bromo-2-ethoxyphenyl)cyclopropanecarbonitrile 
• 1385022-71-8 5-(4-ethoxy-3-methylphenyl)-1H-indole 
• 1385022-73-0 5-(4-ethoxy-3-methylphenyl)isoquinoline 
• 1385022-69-4 2-(4-ethoxy-3-methylphenyl)pyridine 
• 1310403-97-4 2-(4-ethoxy-3-methylphenyl)-1,3,2-dioxaborolane 
• 1616372-40-7 1-(3'-(3-(1-(4-(tert-butyl)benzyl)-4-ethyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)propyl)-4-ethoxy-[1,1'-biphenyl]-3-yl)cyclopropanecarboxylic acid 

Relevant academic research and scientific papers

TRIAZOLONE COMPOUNDS AND USES THEREOF

The invention disclosed herein is directed to compounds of Formula I [Formula should be inserted here] and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leuke

TRIAZOLONE COMPOUNDS AND USES THEREOF

The invention disclosed herein is directed to compounds of Formula (I) and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula (I), or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, colon, pancreatic, chronic lymphocytic leukemia, melanoma and other cancers comprising administration of a of a therapeutically effective amount of a selective PPARα antagonist. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infections and HIV infections. The invention disclosed herein is also directed to a methods of preventing the onset of and/or recurrence of acute and chronic myeloid leukemia, as well as other cancers, comprising administration of a of a therapeutically effective amount of a selective PPARα antagonist.

4,5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES

The present invention relates to a compounds of formula I wherein R1, R1′, R2, R3, R4, X, Ar, and m are as defined in the specification and claims and pharmaceutically active acid addition salts thereof. Compounds of the invention have Asp2 (β-secretase, BACE 1 or Memapsin-2) inhibitory activity and are useful for the treatment of diseases characterized by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.