797050-69-2

Upstream product

• 151054-77-2 1-benzylindole-2,3-dicarboxylic anhydride 
• 797050-65-8 1-benzyl-3-(2,4,6-trimethoxynicotinoyl)indole-2-carboxylic acid 
• 797050-67-0 1-benzyl-3-(2-hydroxy-4,6-dimethoxynicotinoyl)indole 
• 91591-88-7 2,4,6-trimethoxypyridine 
• 75-16-1 methylmagnesium bromide 
• 797050-68-1 1-benzyl-3-(4,6-dimethoxy-2-trifluoromethanesulfonyloxynicotinoyl)indole 

Downstream Products

• 797050-70-5 (1-benzyl-1H-indol-3-yl)-(4-hydroxy-6-methoxy-2-methyl-pyridin-3-yl)-methanone 

Relevant academic research and scientific papers

Synthesis of 3-methoxyolivacine and olivacine by Friedel-Crafts reaction of indole-2,3-dicarboxylic anhydride with 2,4,6-trimethoxypyridine

1-Benzylindole-2,3-dicarboxylic anhydride (1) was reacted with 2,4,6-trimethoxypyridine in the presence of titanium(IV) chloride to give 3-(2,4,6-trimethoxynicotinoyl)indole-2-carboxylic acid (2) as the sole product in high yield, which could be converted