799244-00-1

Upstream product

• 171178-44-2 6-fluoro-4-oxo-3H-pyrido[3,4-d]pyrimidine 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 455-88-9 5-nitro-2-fluorotoluene 
• 138227-69-7 1-tert-butyloxycarbonyl-4-(4-amino-2-methylphenyloxy)piperidine 
• 799242-51-6 4-[4-(6-fluoro-pyrido[3,4-d]pyrimidin-4-ylamino)-2-methyl-phenoxy]-piperidine-1-carboxylic acid tert-butyl ester 
• 124-40-3 dimethyl amine 
• 175357-98-9 4-chloro-6-fluoro-pyrido[3,4-d]pyrimidine 

Downstream Products

• 799243-99-5 N₆,N₆-dimethyl-N₄-[3-methyl-4-(piperidin-4-yloxy)-phenyl]-pyrido[3,4-d]pyrimidine-4,6-diamine 

Relevant academic research and scientific papers

The discovery of highly selective erbB2 (Her2) inhibitors for the treatment of cancer

The synthesis and biological evaluation of potent and selective inhibitors of the erbB2 kinase is presented. Based on the 4-anilinoquinazoline chemotype, the syntheses of several new series of erbB2 inhibitors are described with quinazoline and pyrido[4,3