103686-16-4

Basic information

• Product Name: 3-(4-Bromo-2-thienyl)acrylic acid
• Synonyms: trans-3-(4-Bromothiophen-2-yl)acrylic acid
• CAS NO: 103686-16-4
• Molecular Formula: C₇H₅BrO₂S
• Molecular Weight: 233.08
• Product Categories: Building Blocks;C7 to C9;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Thiophenes
• Mol File: 103686-16-4.mol
• Article Data: 10

Chemical Properties

• Melting Point: 168-173℃
• Appearance: /
• CAS DataBase Reference: 3-(4-Bromo-2-thienyl)acrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Bromo-2-thienyl)acrylic acid(103686-16-4)
• EPA Substance Registry System: 3-(4-Bromo-2-thienyl)acrylic acid(103686-16-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 103686-16-4(Hazardous Substances Data)

Usage

General Description

3-(4-Bromo-2-thienyl)acrylic acid is a chemical compound with the molecular formula C7H5BrO2S. It is a derivative of acrylic acid, with a 3-(4-Bromo-2-thienyl) group attached to the carbon-carbon double bond. 3-(4-Bromo-2-thienyl)acrylic acid is commonly used in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of specialty polymers and materials. It has also been studied for its potential use in organic light-emitting diodes (OLEDs) and other electronic applications. 3-(4-Bromo-2-thienyl)acrylic acid is considered to be a valuable building block in organic synthesis, with a range of potential applications in various industries.

Upstream product

• 110-89-4 piperidine 
• 18791-75-8 4-Bromothiophen-2-aldehyde 
• 98-03-3 thiophene-2-carbaldehyde 
• 141-82-2 malonic acid 

Downstream Products

• 154593-57-4 (S)-2-amino-3-(4-bromothiophen-2-yl)propanoic acid 
• 869776-29-4 N,N'-di(p-bromophenyl)-3,6-dichlorothieno[2,3-b:2',3'-d]thiophene-2,5-dicarboxamide 
• 29064-82-2 3-bromo-4-chloro-[3,2-c]-thienopyridine 
• 799293-92-8 4-amino-3-bromo-7-(3,4,5-trimethoxyphenyl)thieno[3,2-c]pyridine 
• 799293-87-1 4-amino-7-bromo-3-(3-chloro-4-fluorophenyl)-thieno[3,2-c]pyridine 
• 799293-86-0 4-amino-3-(3-chloro-4-fluoro-phenyl)-thieno[3,2-c]pyridine 

Relevant articles and documents

Discovery of thienopyridines as Src-family selective Lck inhibitors

We describe the identification, SAR, and in vivo pharmacology of a new series of Src-family selective Lck inhibitors. These thienopyridines were designed based on a desire to access the unique residues in the extended hinge region of Lck.

NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A

The present invention relates to novel compounds of the formula I which are inhibitors of phosphodiesterase type 10A and to their use for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders

Improved synthesis of 3-substituted-4-amino-[3,2-c]-thienopyridines

(Chemical Equation Presented) Two syntheses of 3-substituted-4-amino-[3,2- c]thienopyridines have been developed to replace the standard literature route to these compounds, which uses unattractive conditions involving azide and high temperatures. The fir