80228-22-4

Basic information

• Product Name: (E)-2-benzylidene-3,3-dimethylbutanoic acid
• Synonyms: (E)-2-benzylidene-3,3-dimethylbutanoic acid
• CAS NO: 80228-22-4
• Molecular Weight: 204.269
• Mol File: 80228-22-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (E)-2-benzylidene-3,3-dimethylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-benzylidene-3,3-dimethylbutanoic acid(80228-22-4)
• EPA Substance Registry System: (E)-2-benzylidene-3,3-dimethylbutanoic acid(80228-22-4)

Safety Data

• Hazardous Substances Data: 80228-22-4(Hazardous Substances Data)

Upstream product

• 30263-65-1 1,1-dibromo-3,3-dimethylbutan-2-one 
• 100-52-7 benzaldehyde 
• 5340-78-3 ethyl 3,3-dimethylbutanoate 
• 124-38-9 carbon dioxide 
• 4250-82-2 (3,3-dimethyl-but-1-ynyl)benzene 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 73378-20-8 cis-3-tert-butyl-4-phenyloxetan-2-one 

Downstream Products

• 56407-99-9 (E)-2-benzylidene-3,3-dimethylbutan-1-ol 

Relevant articles and documents

HAMMETT-CORRELATIONS, SOLVENT EFFECTS AND STEREOCHEMISTRY OF THE THERMAL DECARBOXYLATION OF 2-OXETANONES - EVIDENCE FOR A ZWITTERIONIC INTERMEDIATE

Kinetic and stereochemical data of the thermal decarboxylation of 2-oxetanones (1 and 2) indicate that the reaction proceeds via a zwitterionic intermediate Z.

Cp2TiCl2-catalyzed hydrocarboxylation of alkynes with CO2: formation of α,β-unsaturated carboxylic acids

Cp2TiCl2-catalyzed hydrocarboxylation of alkynes with CO2 (atmospheric pressure) has been reported. A range of alkynes were transformed to the corresponding α,β-unsaturated carboxylic acids in high yields with high regioselectivity. The reaction proceeded with hydrotitanation, transmetalation, and subsequently carboxylation with CO2

A highly stereoselective synthesis of tri- and tetrasubstituted olefins via ynolates

A highly stereoselective synthesis of tri- and tetrasubstituted olefins has been accomplished by the reactions of ynolates with aldehydes and ketones.