802983-90-0Relevant academic research and scientific papers
Novel one pot synthesis of polysubstituted pyrazolo[1,5-a]- and imidazo[1,2-a]pyrimidines
Kiselyov, Alexander S.,Smith II, Leon
, p. 2611 - 2614 (2006)
We have described a convenient regioselective one-pot approach to pyrazolo[1,5-a]- and imidazo[1,2-a]pyrimidine derivatives from α,β-unsaturated imines generated in situ and amino heterocycles. Reaction is general with respect to all three components, nam
A metal-free regioselective multicomponent approach for the synthesis of free radical scavenging pyrimido-fused indazoles and their fluorescence studies
Palaniraja, Jeyakannu,Roopan, Selvaraj Mohana,Rayalu, G. Mokesh,Al-Dhabi, Naif Abdullah,Arasu, Mariadhas Valan
, (2016/12/03)
This study deals with a new and efficient metal-free regioselective synthesis of pyrimido-fused indazoles with nitrogen ring junction motifs. We have developed a metal-free domino type reaction between 3-aminoindazole, aryl aldehydes and aceotophenones in the presence of KOH/DMF that leads to pyrimido[1,2-b]indazole analogues. Response Surface Methodology (RSM) coupled with a Box-Behnken design (BBD) were utilized for exploring the effect of base used (A), temperature of reaction (B) and (C), reaction time. This approach can allow access to a variety of pyrimidoindazole fluorophores and related compounds. The compound N,N-dimethyl-4-(2-phenylpyrimido[1,2-b]indazol-4-yl)aniline (4e) displays the maximum fluorescence intensity at 518 nm and shows a fluorescence quantum yield of 0.068. The synthesized pyramido-fused indazoles have been evaluated for their free radical scavenging activity and compound 4f showed good antioxidant activity.
ORGANIC COMPOUND AND ORGANIC ELECTRO LUMINESCENCE DEVICE COMPRISING THE SAME
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Paragraph 0087-0091, (2016/10/10)
The present invention relates to: a novel compound having an excellent light-emitting ability; and an organic electroluminescent element having improved characteristics such as light-emitting efficiency, driving voltage, and lifespan since at least one organic layer thereof contains the compound.
One-pot synthesis of highly functionalized pyrimido[1,2-b]indazoles via 6-endo-dig cyclization
Palaniraja, Jeyakannu,Roopan, Selvaraj Mohana,Rayalu, G. Mokesh
, p. 24610 - 24616 (2016/03/15)
An efficient synthesis of nitrogen ring junction pyrimido-indazoles has been developed. This is a metal catalyzed transformation that proceeds via A3 coupling reaction between 1H-indazol-3-amine, aromatic aldehydes and alkynes, which undergoes
Carbon-Carbon Bond Cleavage Reaction: Synthesis of Multisubstituted Pyrazolo[1,5-a]pyrimidines
Saikia, Pallabi,Gogoi, Sanjib,Boruah, Romesh C
, p. 6885 - 6889 (2015/10/06)
A new carbon-carbon bond cleavage reaction was developed for the efficient synthesis of multisubstituted pyrazolo[1,5-a]pyrimidines. This base induced reaction of 1,3,5-trisubstituted pentane-1,5-diones and substituted pyrazoles afforded good yields of the pyrazolo[1,5-a]pyrimidines.
Synthesis of 5,7-diarylpyrazolo[1,5-a]pyrimidines via KOH mediated tandem reaction of 1H-pyrazol-3-amines and chalcones
Kaswan, Pinku,Pericherla, Kasiviswanadharaju,Purohit, Deepshikha,Kumar, Anil
supporting information, p. 549 - 553 (2015/02/19)
An efficient and facile protocol has been developed for the synthesis of pyrazolo[1,5-a]pyrimidines through the tandem reaction of 3-aminopyrazoles and chalcones in the presence of catalytic amounts of KOH. The reported method offers access to 5,7-diarylp
Convenient synthesis of substituted 3-alkenylpyrazolo[1,5-a]pyrimidines via Heck cross-coupling reaction
Yin, Lunxiang,Liebscher, Juergen
, p. 2329 - 2334 (2007/10/03)
3-Iodopyrazolo[1,5-a]pyrimidines 3 were easily obtained by direct iodination of pyrazolo[1,5-a]pyrimidines 2 with NIS and could be transformed into a series of new substituted 3-alkenyl-pyrazolo[1,5-a]pyrimidines 5 by Heck cross-coupling.
