80360-17-4Relevant academic research and scientific papers
SYNTHESIS OF 1-(PHENYLSULFONYL)INDOL-3-YL TRIFLUOROMETHANESULFONATE
Conway, Samuel C.,Gribble, Gordon W.
, p. 627 - 633 (2007/10/02)
The synthesis of the potentially useful intermediate 1-(phenylsulfonyl)indol-3-yl trifluoromethanesulfonate (triflate) (1), via several approaches to the corresponding indoxyl 6, is decsribed.Of these, the direct oxidation of 1-(phenylsulfonyl)indole (2)
Generation and Reactions of 3-Lithio-1-(phenylsulfonyl)indole
Saulnier, Mark G.,Gribble, Gordon W.
, p. 757 - 761 (2007/10/02)
Treatment of 1-(phenylsulfonyl)-3-iodoindole (6) with 2 equiv of tert-butyllithium (-100 deg C THF) generates essentially quantitatively 3-lithio-1-(phenylsulfonyl)indole (1).Quenching 1 with various electrophiles gives 3-substituted indoles in good yield
