803684-08-4Relevant academic research and scientific papers
Convergent total synthesis of squamostolide
Quinn, Kevin J.,Smith, Austin G.,Cammarano, Carolyn M.
, p. 4881 - 4886 (2008/02/01)
A convergent total synthesis of the Annonaceous acetogenin squamostolide, in a longest linear sequence of nine steps from d-mannitol, is reported. Central to the efficiency of the synthesis is a highly selective tandem ring-closing/cross metathesis step in which lactone formation and fragment coupling are accomplished.
Concise total synthesis of (-)-muricatacin by tandem ring-closing/cross metathesis
Quinn, Kevin J.,Isaacs, Andre K.,Arvary, Rebecca A.
, p. 4143 - 4145 (2007/10/03)
(Chemical Equation Presented) A strategy for the synthesis of chiral 5-(1-hydroxyalk-2-enyl)-5H-furan-2-ones and its application to the total synthesis of (-)-muricatacin, in four steps and 37% overall yield from (R,R)-hexa-1,5-diene-3,4-diol, are describ
