80458-94-2

Basic information

• Product Name: 1H-2-Benzopyran-1-one, 8-hydroxy-3-(4-hydroxyphenyl)-
• CAS NO: 80458-94-2
• Molecular Formula: C15H10O4
• Molecular Weight: 254.242
• Mol File: 80458-94-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzopyran-1-one, 8-hydroxy-3-(4-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran-1-one, 8-hydroxy-3-(4-hydroxyphenyl)-(80458-94-2)
• EPA Substance Registry System: 1H-2-Benzopyran-1-one, 8-hydroxy-3-(4-hydroxyphenyl)-(80458-94-2)

Safety Data

• Hazardous Substances Data: 80458-94-2(Hazardous Substances Data)

Upstream product

• 507480-02-6 5-(bromomethyl)-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one 
• 95307-62-3 α-(4-benzyloxyphenyl)-α-morpholinoacetonitrile 
• 1137-31-1 2-carboxy-3-methoxybenzene-1-acetic acid 
• 42421-12-5 (2-carboxy-3-hydroxyphenyl)acetic acid 
• 1214-87-5 methyl (2-carbomethoxy-3-methoxyphenyl)acetate 
• 183619-44-5 8-(tert-Butyl-dimethyl-silanyloxy)-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-isochroman-1-one 
• 113345-85-0 3,4'-dimethyl-2-carboxystilbene 
• 113345-84-9 methyl 2-methoxy-6-[2-(4-methoxyphenyl)ethenyl]benzoate 
• 491-79-2 Hydrangeaic acid 
• 480-47-7 hydrangenol 
• 183619-48-9 8-(tert-Butyl-dimethyl-silanyloxy)-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-isochromen-1-one 
• 36640-12-7 3-(4-methoxyphenyl)-7-methoxy-2-benzopyran-1(1H)-one 
• 100-07-2 4-methoxy-benzoyl chloride 

Relevant articles and documents

Inhibition of the enzymes in the leukotriene and prostaglandin pathways in inflammation by 3-aryl isocoumarins

The biosynthesis of leukotrienes in one of the arachidonic acid pathways and PGE2in the other by 5-LOX and mPGES1 respectively, play pivotal roles in augmenting inflammatory responses. PGE2is known to participate in cancer pathologic

Development of bioactive functions in Hydrangeae Dulcis Folium. VI. Syntheses of thunberginols A and F and their 3'-deoxy-derivatives using regiospecific lactonization of stilbene carboxylic acid: Structures and inhibitory activity on histamine release of hydramacrophyllols A and B

Lactonization reaction of 2-carboxystilbene mediated by copper(II) chloride proceeded regiospecifically to give the five-membered lactone, while the bromolactonizations using N-bromosuccinimide and anodic oxidation were found to furnish the six-membered lactone. Using these regiospecific lactonization reactions as a key step, antiallergic and antimicrobial isocoumarins and the benzylidenephthalides thunberginols A and F and their 3'-deoxyanalogs were synthesized from phyllodulcin and hydrangenol. Two phthalides called hydramacrophyllols A and B were isolated from Hydrangeae Dulcis Folium and their stereostructures were determined on the basis of physicochemical and chemical evidence, which included the syntheses of hydramacrophyllols A and B from hydrangenol by the application of the lactonization method using copper(II) chloride. In addition, hydramacrophyllols A and B were found to exhibit an inhibitory effect on the histamine release from rat peritoneal exudate cells induced by antigen- antibody reaction.

Syntheses of antifungal isocoumarins. II. Synthesis and antifungal activity of 3-substituted isocoumarins

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