80625-18-9

Basic information

• Product Name: METHYL 2-AMINO-5-PHENYL-1,3-THIAZOLE-4-CARBOXYLATE
• Synonyms: 4-Thiazolecarboxylic acid, 2-amino-5-phenyl-, methyl ester;2-Amino-5-phenyl-4-thiazolecarboxylic acid methyl ester;2-Amino-5-phenyl-thiazole-4-carboxylic acid methyl ester
• CAS NO: 80625-18-9
• Molecular Formula: C₁₁H₁₀N₂O₂S
• Molecular Weight: 234.27
• Mol File: 80625-18-9.mol
• Article Data: 17

Chemical Properties

• Melting Point: 223℃
• Appearance: /
• Density: 1.319
• CAS DataBase Reference: METHYL 2-AMINO-5-PHENYL-1,3-THIAZOLE-4-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-AMINO-5-PHENYL-1,3-THIAZOLE-4-CARBOXYLATE(80625-18-9)
• EPA Substance Registry System: METHYL 2-AMINO-5-PHENYL-1,3-THIAZOLE-4-CARBOXYLATE(80625-18-9)

Safety Data

• Hazardous Substances Data: 80625-18-9(Hazardous Substances Data)

Usage

General Description

Methyl 2-amino-5-phenyl-1,3-thiazole-4-carboxylate is a chemical compound with the molecular formula C12H11N3O2S. It is a thiazole derivative that contains an amino group, a phenyl group, and a carboxylate group. METHYL 2-AMINO-5-PHENYL-1,3-THIAZOLE-4-CARBOXYLATE has potential applications in medicinal chemistry and pharmaceutical research due to its structural features, which make it a promising candidate for the development of new drugs. Additionally, it may also have uses in other fields such as organic synthesis and materials science. Further research on the properties and potential applications of methyl 2-amino-5-phenyl-1,3-thiazole-4-carboxylate is warranted to fully understand its capabilities and limitations.

Upstream product

• 115174-39-5 2-Amino-5-phenyl-thiazole-4-carboxylic acid methyl ester; hydrochloride 
• 93439-36-2 2-Chlor-2,3-epoxy-3-phenyl-propionsaeure-methylester 
• 17356-08-0 thiourea 
• 32803-73-9 methyl 3-phenyl-3-chloro-2-ketopropionate 
• 100-52-7 benzaldehyde 
• 98-80-6 phenylboronic acid 
• 914349-71-6 5-bromo-2-tert-butoxycarbonylamino-thiazole-4-carboxylic acid methyl ester 
• 116-54-1 dichloroacetic acid methyl ester 
• 67-56-1 methanol 
• 535-15-9 ethyl 1,1-dichloroacetate 

Downstream Products

• 99972-45-9 methyl 5-phenylthiazole-4-carboxylate 
• 80625-19-0 methyl 5-phenyl-2-chloro-4-thiazolecarboxylate 
• 802276-49-9 2-amino-5-phenyl-thiazole-4-carboxylic acid 
• 127918-95-0 t-butyl [2-(2-chloro-5-phenyl-4-thiazolecarboxamido)ethyl]carbamate 
• 127919-00-0 methyl 2-bromo-5-phenyl-1,3-thiazole-4-carboxylate 
• 737824-35-0 methyl 2-(acetylamino)-5-phenyl-1,3-thiazole-4-carboxylate 
• 13743-14-1 5-phenyl-1,3-thiazole-4-carboxylic acid 

Relevant articles and documents

Competition of the Hantzsch and Boese reactions in the interaction of 1-thiocarbamoylthiosemicarbazide and phenylchloropyruvic acid methyl ester

1-Thiocarbamoylthiosemicarbazide, the synthetic equivalent of thiourea and thiosemicarbazide, reacts with phenylchloropyruvic acid methyl ester exclusively as thiourea (Hantzsch reaction) forming 2-hydrazo-4-methoxycarbonyl-5-phenylthiazole. Diacetylation

SUBSTITUTED 2-AZABICYCLO[3.1.1]HEPTANE AND 2-AZABICYCLO[3.2.1]OCTANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS

There is provided a compound of formula (I), wherein L1 to L3, R1 to R4, X, A and B have meanings given in the description, and pharmaceutically acceptable salts, solvates and prodrugs thereof, which compounds are useful as antagonists of the orexin-1 and orexin-2 receptors or as selective antagonists of the orexin-1 receptor, and thus, in particular, in the treatment or prevention of inter alia substance dependence, addiction, anxiety disorders, panic disorders, binge eating, compulsive disorders, impulse control disorders, cognitive impairment and Alzheimer's disease.

Novel Thiazole Carboxylic Acid derivatives possessing a "zinc Binding Feature" as Potential human glyoxalase-I inhibitors

Glyoxalase-I (Glo-I) enzyme is an attractive new target for developing new cancer therapeutics. This enzyme is a dimeric mononuclear zinc coordinating metalloenzyme, and the core zinc ion was utilized in designing potentially active inhibitors possessing