80708-25-4Relevant academic research and scientific papers
5,10-Dihydropyrido-pyrazolo-triazine compounds and application thereof
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Paragraph 0103; 0104; 0105, (2017/08/02)
The invention relates to 5,10-dihydropyrido[2',3':5,6]pyrazolo[2,3-e][1,2,4]triazine compounds shown in general formula I, and their optical activators or racemates or their pharmaceutically acceptable salts, hydrates or solvates, wherein substituents R1,
Quinoxalinones
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Page/Page column 12, (2010/02/12)
The invention features quinoxalinones, pharmaceutical compositions containing them and methods of using them to treat, for example, diabetes.
Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors
Dudash Jr., Joseph,Zhang, Yongzheng,Moore, John B.,Look, Richard,Liang, Yin,Beavers, Mary Pat,Conway, Bruce R.,Rybczynski, Philip J.,Demarest, Keith T.
, p. 4790 - 4793 (2007/10/03)
A series of 3-anilino-quinoxalinones has been identified as a new class of glycogen phosphorylase inhibitors. The lead compound 1 was identified through high throughput screening as well as through pharmacophore-based electronic screening. Modifications were made to the scaffold of 1 to produce novel analogues, some of which are 25 times more potent than the lead compound.
Tricyclic heterocyclic compounds as psychopharmaceuticals
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, (2008/06/13)
New heterocyclic compounds having the general formula STR1 wherein STR2 CO2 R' or CONR'R", wherein R' and R" independently are C1-6 -alkyl, C3-7 -cycloalkyl or C1-6 -alkoxymethyl; --A-- is --C(=O)--NR'"--, --NR'"--C(=O)--, or STR3 wherein R'" is C1-6 -alkyl; X is C or N; and R4 is hydrogen, halogen, CN, C1-6 -alkyl, C1-6 -alkynyl, trimethylsilyl-C1-6 -alkynyl, aryloxy which may be substituted with halogen, aralkoxy, C3-7 -cycloalkoxy which may be substituted with one or more C1-6 -alkyl groups, or NR""R'"", wherein R"" and R'"" independently are C1-6 -alkoxy or together with the nitrogen atom form a 3-7 membered heterocyclic ring. The compounds are useful in psychopharmaceutical preparations as anticonvulsants, anxiolytics, hypnotics, and nootropics.
Thiazoloquinoxalin-1,4-diones for treating allergy
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, (2008/06/13)
New triazoloquinoxalin-1,4-diones are described as well as the use thereof as anti-allergenic agents.
