80729-00-6

Upstream product

• 17496-14-9 2,3-dihydro-2-methyl-1H-inden-1-one 
• 100-58-3 phenylmagnesium bromide 
• 5445-77-2 2-benzylpropionaldehyde 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 93-55-0 1-phenyl-propan-1-one 
• 252935-81-2 3-(2-bromo-phenyl)-2-methyl-1-phenyl-propan-1-one 
• 101-39-3 2-methyl-3-phenyl-2-propenal 
• 1009-67-2 2-methyl-3-phenylpropanoic acid 

Downstream Products

• 35099-60-6 2-methyl-3-phenylindene 
• 52218-33-4 2,3-dihydro-2-methyl-3-phenylindene 

Relevant academic research and scientific papers

HYDROGENATION REACTIONS WITH HYDRIDOCOBALT TETRACARBONYL

The tetrasubstituted ethylene, bifluorenylidene, reacts very rapidly (4.06*10-2 l mol-1 sec-1 at 0 deg C) with HCo(CO)4 to give bifluorenyl. α-Phenylacrylonitrile (atroponitrile) reacts even more rapidly under the same conditions (6.0 l mol-1 sec-1).Other highly substituted ethylenes react very slowly with HCo(CO)4, indicating considerable steric effects.The data are consistent with radical type intermediates.

B(C6F5)3-Catalyzed Highly Stereoselective Hydrogenation of Unfunctionalized Tetrasubstituted Olefins

A metal-free hydrogenation of unfunctionalized tetrasubstituted olefins were successfully realized using a combination of B(C6F5)3 and Ph2NMe catalyst. The corresponding products were afforded in 58-98% yields with up to >99:1 cis/trans selectivity.

Efficient synthesis of 2- and 3-substituted indenes from 2-bromobenzyl bromide through an enolate alkylation/Cr(II)/Ni(II)-mediated carbonyl addition sequence

An efficient new synthesis of 2- and 3-substituted indenes has been developed based on the nickel-catalyzed chromium(II)-promoted addition of aryl bromides to a tethered ketone carbonyl. Several tethered bromoaryl ketones were prepared through enolate alk