808172-50-1

Basic information

• Product Name: 2-Pyrrolidinone, 5-(2-hydroxyethyl)-, (5S)-
• CAS NO: 808172-50-1
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.159
• Mol File: 808172-50-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Pyrrolidinone, 5-(2-hydroxyethyl)-, (5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone, 5-(2-hydroxyethyl)-, (5S)-(808172-50-1)
• EPA Substance Registry System: 2-Pyrrolidinone, 5-(2-hydroxyethyl)-, (5S)-(808172-50-1)

Safety Data

• Hazardous Substances Data: 808172-50-1(Hazardous Substances Data)

Upstream product

• 66673-40-3 (R)-5-hydroxymethylpyrrolidin-2-one 
• 98134-78-2 (R)-2-(5-oxopyrrolidin-2-yl)acetonitrile 
• 128899-31-0 <(2R)-5-oxopyrrolidin-2-yl>methyl 4-methylbenzenesulfonate 
• 17342-08-4 (S)-Pyroglutaminol 
• 51693-17-5 (S)-toluene-4-sulfonic acid 5-oxo-pyrrolidin-2-ylmethyl ester 
• 72479-06-2 2-[(2S)-5-oxopyrrolidin-2-yl]acetonitrile 
• 124201-75-8 (S)-(5-oxo-pyrrolidin-2-yl)-acetic acid ethyl ester 
• 67036-44-6 methyl (S)-2-(5-oxopyrrolidin-2-yl)acetate 
• 4931-66-2 methyl (S)-pyroglutamate 
• 881405-69-2 (2S)-2-methoxycarbonylmethyl-5-oxopyrrolidine-1-carboxylic acid tert-butyl ester 
• 881405-70-5 (2R)-2-methoxycarbonylmethyl-5-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester 
• 881405-68-1 (2S)-2-methoxycarbonylmethyl-5-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester 
• 572889-82-8 (1R,5R,6R)-2-tert-butyl 6-methyl 2-azabicyclo[3.1.0]hex-3-ene-2,6-dicarboxylate 
• 321133-39-5 (-)-2-azabicyclo[3.1.0]hex-3-ene-2,6-dicarboxylic acid 2-tert-butyl ester 6-methyl ester 

Downstream Products

• 143771-06-6 (-)-(S)-2-(2-hydroxyethyl)pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE

Described herein are new, selective modulators of the 5 -HT7 receptor. These selective compounds can be useful for the treatment of CNS and non-CNS indications. Compounds described herein can be selective in targeting 5-HT7 receptors

5-HT7 Receptor Antagonists with an Unprecedented Selectivity Profile

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Total synthesis of (-)-martinellic acid

An enantioselective formal total synthesis of the pyrrolo[3,2-c]quinoline natural product martinellic acid has been achieved. The key steps involve a Pd-catalyzed aryl amidation reaction of a pyrroglutamate derivative, an intramolecular [3+2] azomethine ylide-alkene cycloaddition and a reductive ring opening reaction.