98134-78-2

Basic information

• Product Name: (5-OXOPYRROLIDIN-2-YL)ACETONITRILE
• Synonyms: (5-OXOPYRROLIDIN-2-YL)ACETONITRILE;[5-oxo-2-pyrrolidinyl]acetonitrile
• CAS NO: 98134-78-2
• Molecular Formula: C6H8N2O
• Molecular Weight: 124.14052
• Mol File: 98134-78-2.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (5-OXOPYRROLIDIN-2-YL)ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (5-OXOPYRROLIDIN-2-YL)ACETONITRILE(98134-78-2)
• EPA Substance Registry System: (5-OXOPYRROLIDIN-2-YL)ACETONITRILE(98134-78-2)

Safety Data

• Hazardous Substances Data: 98134-78-2(Hazardous Substances Data)

Usage

General Description

(5-OXOPYRROLIDIN-2-YL)ACETONITRILE is a chemical compound with the molecular formula C6H8N2O. It is a nitrile derivative with a pyrrolidin-2-one moiety, which is commonly used as an intermediate in the synthesis of various pharmaceutical and agrochemical products. It is a colorless to pale yellow liquid with a slightly sweet odor, and it is soluble in water and most organic solvents. (5-OXOPYRROLIDIN-2-YL)ACETONITRILE is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals due to its versatile reactivity and functional group compatibility. It is also used as a research chemical for the development of new compounds with potential therapeutic or agricultural applications.

Upstream product

• 98-79-3 L-Pyroglutamic acid 
• 773837-37-9 sodium cyanide 
• 128899-31-0 <(2R)-5-oxopyrrolidin-2-yl>methyl 4-methylbenzenesulfonate 
• 4042-36-8 D-pyrrolidone-5-carboxylic acid 
• 66673-40-3 (R)-5-hydroxymethylpyrrolidin-2-one 
• 51693-17-5 (S)-toluene-4-sulfonic acid 5-oxo-pyrrolidin-2-ylmethyl ester 
• 4931-66-2 methyl (S)-pyroglutamate 
• 56-86-0 L-glutamic acid 
• 17342-08-4 (S)-Pyroglutaminol 
• 151-50-8 potassium cyanide 
• 72479-05-1 (S)-(-)-5-(Bromomethyl)-2-pyrrolidinone 
• 93288-20-1 [(2S)-5-oxopyrrolidin-2-yl]methyl methanesulfonate 
• 7149-65-7 ethyl (S)-pyroglutamate 
• 143-33-9 sodium cyanide 

Downstream Products

• 808172-50-1 (R)-5-(2-hydroxyethyl)pyrrolidin-2-one 

Relevant articles and documents

NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE

Described herein are new, selective modulators of the 5 -HT7 receptor. These selective compounds can be useful for the treatment of CNS and non-CNS indications. Compounds described herein can be selective in targeting 5-HT7 receptors

NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE

Pharmaceutical compositions of the invention comprise functionalized lactam derivatives of formula (I) having a disease-modifying action in the treatment of diseases associated with dysregulation of 5- hydroxytryptamine receptor 7 activity. A is selected

BETA-LACTAMASE INHIBITOR COMPOUNDS

The present invention is directed to compounds which are beta-lactamase inhibitors. The compounds and their pharmaceutically acceptable salts are useful in combination with beta- lactam antibiotics, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of R1, R2, R3, R4, R5 and R6 are described herein.