80866-77-9

Usage

Uses

Used in Organic Synthesis:
2-Chloro-6-nitroanisole is used as a reagent in organic synthesis for its functional groups, which include a chloro group, a nitro group, and a methoxy group. These groups provide points of reactivity, making it a useful compound in the production of other complex molecules.
Used in Pharmaceutical Industry:
2-Chloro-6-nitroanisole is used as an intermediate in the production of pharmaceutical compounds. Its reactivity and functional groups make it a key component in the synthesis of various drugs, contributing to the development of new medications and therapies.
Used in Chemical Research:
2-Chloro-6-nitroanisole is used as a research compound in chemical studies. Its unique properties and reactivity allow scientists to explore new reaction pathways and investigate the behavior of different functional groups in various chemical contexts. This can lead to advancements in our understanding of chemical reactions and the development of new synthetic methods.

InChI:InChI=1/C7H6ClNO3/c1-12-7-5(8)3-2-4-6(7)9(10)11/h2-4H,1H3

Upstream product

• 766-51-8 2-Chloroanisole 
• 603-86-1 2-chloro-6-nitrophenol 
• 77-78-1 dimethyl sulfate 
• 95-51-2 o-chloroaniline 
• 74-83-9 methyl bromide 
• 602-03-9 2,3-dinitroaniline 
• 95-57-8 2-monochlorophenol 
• 123-91-1 1,4-dioxane 
• 67-56-1 methanol 
• 90352-49-1 (2-chloro-6-nitro-phenyl)-p-tolyl sulfone 
• 124-41-4 sodium methylate 
• 602-02-8 2,3-dinitrochlorobenzene 
• 3209-22-1 1,2-Dichloro-3-nitrobenzene 

Downstream Products

• 143359-97-1 acetic acid-(3-chloro-2-methoxy-anilide) 
• 51114-68-2 3-chloro-2-methoxyaniline 

Relevant academic research and scientific papers

Preparation method of Eltrombopag

The invention discloses a preparation method of Eltrombopag. The chemical name of Eltrombopag is 3-{(2Z)-2-[1-(3,4-xylyl)-3-methyl-5-oxo-1,5-dihydro-4H-parazole-4-ylidene]diazanyl}-2-hydroxy-3-biphenylcarboxylic acid-2-aminoethanol salt. The process of the preparation technique of the preparation method of Eltrombopag is simple, materials are easy to obtain, and the preparation method of Eltrombopag is cost-efficient and environment-friendly, can help realize industrialization, can promote the economic and technological development of the Eltrombopag active pharmaceutical ingredient, reduce the production cost, and is suitable for mass production.

A 2-chloro-6-fluoro anisole and wherein the intermediate preparation method

The invention discloses a method for preparing 2-chlorine-6-fluoroanisole and midbodies of the 2-chlorine-6-fluoroanisole. The method for preparing the 2-chlorine-6-fluoroanisole comprises the following step that under the condition that the temperature ranges from 100 DEG C to 150 DEG C, a cleavage reaction is conducted on a compound shown as the formula V. A method for preparing a compound shown as the formula III comprises the following step that in a solvent and under catalysis of platinum carbon, a reduction reaction is conducted on a compound shown as the formula II and hydrogen, so that the compound shown as the formula III is obtained. A method for preparing the compound shown as the formula II comprises the following step that in a solvent and under catalysis of a catalyst, an etherification reaction is conducted on a compound shown as the formula I and sodium methylate, so that the compound shown as the formula II is obtained. According to the method for preparing the 2-chlorine-6-fluoroanisole, raw materials are low in price and easy to obtain, the production cost is low, reaction conditions are gentle, the yield is high, and the method is suitable for industrialized production.