80866-77-9

Basic information

• Product Name: 2-CHLORO-6-NITROANISOLE
• Synonyms: 3-Chloro-2-methoxynitrobenzene 98%;3-Chloro-2-methoxynitrobenzene;3-Chloro-2-methoxy-1-nitrobenzene;Einecs 279-580-4;Anisole, 2-chloro-6-nitro-;Benzene, 1-chloro-2-methoxy-3-nitro-;ST012276;3-Chloro-2-methoxynitrobenzene98%
• CAS NO: 80866-77-9
• Molecular Formula: C₇H₆ClNO₃
• Molecular Weight: 187.58
• EINECS: 279-580-4
• Product Categories: blocks;NitroCompounds;Miscellaneous
• Mol File: 80866-77-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 276.7 °C at 760 mmHg
• Flash Point: 121.1 °C
• Appearance: /
• Density: 1.366 g/cm³
• Vapor Pressure: 0.00798mmHg at 25°C
• Refractive Index: 1.559
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-CHLORO-6-NITROANISOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-6-NITROANISOLE(80866-77-9)
• EPA Substance Registry System: 2-CHLORO-6-NITROANISOLE(80866-77-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 80866-77-9(Hazardous Substances Data)

Usage

General Description

2-Chloro-6-nitroanisole is a chemical compound that primarily acts as an intermediate in the production of several other complex compounds. It plays a significant role in organic synthesis due to its functional groups, which include a chloro group, a nitro group, and a methoxy group. These groups are often points of reactivity, making 2-Chloro-6-nitroanisole a useful reagent. Despite this, there is limited information on potential health effects or hazards associated with the compound, which underscores the need to handle it with care, particularly to avoid inhalation and skin or eye contact while using the material.

InChI:InChI=1/C7H6ClNO3/c1-12-7-5(8)3-2-4-6(7)9(10)11/h2-4H,1H3

Upstream product

• 95-51-2 o-chloroaniline 
• 74-83-9 methyl bromide 
• 603-86-1 2-chloro-6-nitrophenol 
• 95-57-8 2-monochlorophenol 
• 123-91-1 1,4-dioxane 
• 67-56-1 methanol 
• 90352-49-1 (2-chloro-6-nitro-phenyl)-p-tolyl sulfone 
• 124-41-4 sodium methylate 
• 77-78-1 dimethyl sulfate 
• 3209-22-1 1,2-Dichloro-3-nitrobenzene 
• 766-51-8 2-Chloroanisole 
• 602-02-8 2,3-dinitrochlorobenzene 
• 602-03-9 2,3-dinitroaniline 

Downstream Products

• 143359-97-1 acetic acid-(3-chloro-2-methoxy-anilide) 
• 51114-68-2 3-chloro-2-methoxyaniline 

Relevant articles and documents

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A 2-chloro-6-fluoro anisole and wherein the intermediate preparation method

The invention discloses a method for preparing 2-chlorine-6-fluoroanisole and midbodies of the 2-chlorine-6-fluoroanisole. The method for preparing the 2-chlorine-6-fluoroanisole comprises the following step that under the condition that the temperature ranges from 100 DEG C to 150 DEG C, a cleavage reaction is conducted on a compound shown as the formula V. A method for preparing a compound shown as the formula III comprises the following step that in a solvent and under catalysis of platinum carbon, a reduction reaction is conducted on a compound shown as the formula II and hydrogen, so that the compound shown as the formula III is obtained. A method for preparing the compound shown as the formula II comprises the following step that in a solvent and under catalysis of a catalyst, an etherification reaction is conducted on a compound shown as the formula I and sodium methylate, so that the compound shown as the formula II is obtained. According to the method for preparing the 2-chlorine-6-fluoroanisole, raw materials are low in price and easy to obtain, the production cost is low, reaction conditions are gentle, the yield is high, and the method is suitable for industrialized production.