81-90-3

Basic information

• Product Name: PHENOLPHTHALIN
• Synonyms: PHENOLTHALEIN;PHENOLPHTHALIN;2-[bis(4-hydroxyphenyl)methyl]-benzoicaci;LABOTEST-BB LT00772253;alpha,alpha-bis(4-hydroxyphenyl)-o-toluic acid;PHENOLPHTHALIN,98%;Phenolphthalin, pure, 98%;Benzoic acid, 2-bis(4-hydroxyphenyl)methyl-
• CAS NO: 81-90-3
• Molecular Formula: C₂₀H₁₆O₄
• Molecular Weight: 320.34
• EINECS: 201-384-4
• Mol File: 81-90-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 238 °C
• Boiling Point: 419.24°C (rough estimate)
• Flash Point: 299.7 °C
• Appearance: white glistening fine crystalline powder
• Density: 1.1863 (rough estimate)
• Vapor Pressure: 7.12E-13mmHg at 25°C
• Refractive Index: 1.5400 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: almost transparency in EtOH95vol%
• PKA: 3.96±0.36(Predicted)
• Water Solubility: 175mg/L(20 oC)
• Merck: 14,7244
• CAS DataBase Reference: PHENOLPHTHALIN(CAS DataBase Reference)
• NIST Chemistry Reference: PHENOLPHTHALIN(81-90-3)
• EPA Substance Registry System: PHENOLPHTHALIN(81-90-3)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 81-90-3(Hazardous Substances Data)

Usage

Chemical Properties

white glistening fine crystalline powder

Uses

Different sources of media describe the Uses of 81-90-3 differently. You can refer to the following data:
1. As a reagent for oxidases, blood, HCN, peroxides, copper.
2. Phenolphthalin is used in preparation method of polar polymer doped nanoparticles and composite wave absorbing material containing same.Dyes and metabolite

InChI:InChI=1/C20H16O4/c21-15-9-5-13(6-10-15)19(14-7-11-16(22)12-8-14)17-3-1-2-4-18(17)20(23)24/h1-12,19,21-22H,(H,23,24)/p-1

Upstream product

• 85-44-9 phthalic anhydride 
• 108-95-2 phenol 
• 7647-01-0 hydrogenchloride 
• 21216-19-3 3,3-bis-(4-hydroxy-phenyl)-isoindolin-1-one-imine 
• 7664-93-9 sulfuric acid 
• 5449-84-3 phenolphthalein-4,4'-diyl diacetate 
• 6607-41-6 3,3-bis(4-hydroxyphenyl)-2-phenylisoindolin-1-one 
• 7446-70-0 aluminium trichloride 
• 81-84-5 1,8-Naphthalic anhydride 
• 81-92-5 phenolphthalol 
• 6079-73-8 2-hydroxybenzoylbenzoic acid 
• 79-34-5 1,1,2,2-tetrachloroethane 
• 77-09-8 phenolphthalein 
• 7440-66-6 zinc 

Downstream Products

• 124119-41-1 3,3-bis-(4-isovaleryloxy-phenyl)-phthalide 
• 63450-78-2 ethyl 2-[bis(4-hydroxyphenyl)methyl]benzoate 
• 128102-98-7 3,3-bis-(p-benzyloxyphenyl)phthalide 
• 33964-04-4 dinitrophenolphthalein 
• 151464-30-1 3,3-bis-(4-benzenesulfonyloxy-phenyl)-phthalide 
• 62625-15-4 phenolphthalein dibutyrate 
• 6315-80-6 3,3-bis(4-methoxyphenyl)-3H-isobenzofuran-1-one 
• 114626-60-7 2-(4,4'-dihydroxy-benzhydryl)-benzoic acid butyl ester 
• 386-17-4 3,3-bis(4-hydroxy-3,5-diiodophenyl)isobenzofuran-1(3H)-one 
• 7154-85-0 2-(4-hydroxyphenyl)-1H-isoindole-1,3(2H)-dione 
• 22749-77-5 phenolphthalein N-methyllactam 
• 102079-13-0 dihydrophenolphthalein amide 
• 111272-26-5 2-[bis(4-hydroxyphenyl)methyl]benzohydrazide 
• 79377-41-6 dihydrophenolphthalein N-methylamide 

Relevant articles and documents

Preparation method of carboxylic acid compound

The invention provides a preparation method of a carboxylic acid compound. The preparation method comprises the following step of taking a lactone component to react with hydrogen in the presence of a compound catalyst to obtain the carboxylic acid compound. The compound catalyst comprises a hydrogenation catalyst and Lewis acid. In the presence of the compound catalyst comprising the hydrogenation catalyst and the Lewis acid, the lactone component is subjected to hydrogenation ring-opening reaction to obtain the carboxylic acid compound. The preparation method has the advantages of moderate reaction conditions and high yield; compared with a traditional method, less byproducts are generated, green and chemical requirements are met and the industrial value is better.

METHODS OF MANUFACTURE OF 2-ARYL-3,3-BIS(HYDROXYARYL)PHTHALIMIDINES

A synthetic route for producing a 2-phenyl-3,3-bis(4-hydroxyphenyl)phthalimidine, using a dihydrophenolphthalein intermediate is provided. The dihydrophenolphthalein can be obtained by reduction of a precursor phenolphthalein that is commonly used in the manufacture of phthalimidines. Formation of the dihydrophenolphthalein is followed by activation, amide formation, and oxidation to provide the product phthalimidine

Bisphenols and poly(imidoarylether ketone)s and poly(imidoarylether sulfone)s produced therefrom

Bisphenols having a pendent imide moiety, of formula (I) STR1 in which R1, R2, R3 and R4, which may be the same or different, are selected from hydrogen, fluorine, chlorine, bromine, alkyl of 1 to 6 carbon atoms, aryl of 6 to 10 carbon atoms, alkoxy of 1 to 6 carbon atoms and aryloxy of 6 to 10 carbon atoms; R5 is selected from fluorine, chlorine, bromine and alkyl of 1 to 6 carbon atoms, and m is 0, 1, 2, 3 or 4; and R7 is alkyl of 1 to 18 carbon atoms, aryl of 6 to 10 carbon atoms, unsubstituted or substituted one or more times by a substituent selected from fluorine, chlorine, trifluoromethyl, alkyl of 1 to 6 carbon atoms, and phenyl, or heteroaryl; are useful in producing poly(imidoarylether ketone)s and poly(imidoarylether sulfone)s which are amorphous and are soluble in readily available solvents, while displaying high glass transition temperatures and good thermo-oxidative stability.