81292-68-4

Basic information

• Product Name: 2-Naphthalenecarboxaldehyde, 1,2,3,4-tetrahydro-
• CAS NO: 81292-68-4
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Mol File: 81292-68-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Naphthalenecarboxaldehyde, 1,2,3,4-tetrahydro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Naphthalenecarboxaldehyde, 1,2,3,4-tetrahydro-(81292-68-4)
• EPA Substance Registry System: 2-Naphthalenecarboxaldehyde, 1,2,3,4-tetrahydro-(81292-68-4)

Safety Data

• Hazardous Substances Data: 81292-68-4(Hazardous Substances Data)

Upstream product

• 2208-15-3 4-bromo-3-hydroxy-2-naphthoic acid 
• 5464-07-3 3-acetoxy-2-naphthoic acid 
• 13065-86-6 4-amino-3-hydroxy-[2]naphthoic acid 
• 56961-90-1 4-chloro-3-hydroxy-[2]naphthoic acid 
• 91-13-4 α,α'-dibromo-o-xylene 
• 107-02-8 acrolein 
• 92-70-6 3-Hydroxy-2-naphthoic acid 
• 40685-04-9 1,2,3,4-tetrahydro-2-(hydroxymethylene)naphthalen-1-one 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 1092794-46-1 N,N-dimethyl-1,2,3,4-tetrahydronaphthalene-2-carboxamide 
• 99864-94-5 6,7-dihydro-5H-benzocyclohepten-6-ol 
• 64474-23-3 Benzo-bicyclo<4.1.0>hepten-(3)-ol-(2) 
• 99864-97-8 (1,2-Dihydro-[2]naphthyl)-methanol 
• 22743-31-3 1,2,3,4-tetrahydronaphthalene-carboxylic acid ethyl ester 

Downstream Products

• 91-20-3 naphthalene 
• 34557-54-5 methane 
• 6947-15-5 1,2,3,4-tetrahydro-2-naphthalene methanol 
• 486453-65-0 2-nitro-N-(4-{[(1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-amino]-methyl}-cyclohexylmethyl)-benzenesulfonamide 

Relevant articles and documents

Reduction of N,N-Dimethylcarboxamides to Aldehydes by Sodium Hydride–Iodide Composite

A new and concise protocol for selective reduction of N,N-dimethylamides into aldehydes was established using sodium hydride (NaH) in the presence of sodium iodide (NaI) under mild reaction conditions. The present protocol with the NaH-NaI composite allows for reduction of not only aromatic and heteroaromatic but also aliphatic N,N-dimethylamides with wide substituent compatibility. Retention of α-chirality in the reduction of α-enantioriched amides was accomplished. Use of sodium deuteride (NaD) offers a new step-economical alternative to prepare deuterated aldehydes with high deuterium incorporation rate. The NaH-NaI composite exhibits unique chemoselectivity for reduction of N,N-dimethylamides over ketones.

Probing Intramolecular Electron Transfer in Redox Tag Processes

Herein, we show that redox tag-guided intermolecular formal [2 + 2] cycloaddition can be used as a probe to investigate intramolecular single-electron transfer (SET) mechanisms. The efficacy of intramolecular SET can be evaluated in association with concomitant carbon-carbon bond formation and/or cleavage, leading to cycloaddition or cross-metathesis. Experimental and theoretical results suggest that the intramolecular SET is under both thermodynamic and kinetic control and can also occur through bonds, not only through space.

TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR

Provided are compounds of formula I and formula II or pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The compounds of formula I and formula II or the pharmaceutically acceptable salts of the compounds provide indole 2,3-dioxygenase (IDO) inhibitory activity and are capable of treating IDO-mediated immunosuppressive diseases, such as infectious diseases or cancer.