813-74-1

Basic information

• Product Name: 2,2,3-TRICHLOROPROPIONITRILE
• Synonyms: 2,2,3-TRICHLOROPROPIONITRILE;A,A,B-TRICHLOROPROPIONITRILE;2,2,3-trichloro-propanenitril;2,2,3-trichloro-propionitril;2,2,3-trichlorpropannitril;2,2,3-trichloropropiononitrile;alphaalphabeta-trichloropropionitrile;2,2,3-trichloropropanenitrile
• CAS NO: 813-74-1
• Molecular Formula: C₃H₂Cl₃N
• Molecular Weight: 158.41
• EINECS: 212-388-0
• Mol File: 813-74-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 260.89°C (rough estimate)
• Flash Point: 70.2°C
• Appearance: /
• Density: 1.8997 (rough estimate)
• Vapor Pressure: 0.678mmHg at 25°C
• Refractive Index: 1.6300 (estimate)
• CAS DataBase Reference: 2,2,3-TRICHLOROPROPIONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,3-TRICHLOROPROPIONITRILE(813-74-1)
• EPA Substance Registry System: 2,2,3-TRICHLOROPROPIONITRILE(813-74-1)

Safety Data

• Hazardous Substances Data: 813-74-1(Hazardous Substances Data)

Usage

Safety Profile

A poison by ingestion.Moderately toxic by inhalation. When heated todecomposition it emits toxic vapors of NOx and Clí.

InChI:InChI=1/C3H2Cl3N/c4-1-3(5,6)2-7/h1H2

Upstream product

• 542-76-7 3-Chloropropionitrile 
• 107-13-1 acrylonitrile 
• 920-37-6 2-Chloroacrylonitrile 
• 10151-09-4 (1,1,2,2,3-pentachloro-propyl)-phosphorimidic acid trichloride 
• 7782-50-5 chlorine 
• 875231-35-9 2,3,3-trichloro-propionitrile 

Downstream Products

• 3278-46-4 chloropon 
• 13601-94-0 2,2,3-trichloro-propionic acid amide 
• 920-37-6 2-Chloroacrylonitrile 
• 93140-66-0 phenyl-bis-(2,2,3-trichloro-propionylamino)-methane 
• 6066-06-4 β.β.γ-Trichlor-propylamin 
• 2601-89-0 2,3-dichloropropionitrile 
• 554-68-7 triethylamine hydrochloride 
• 22410-58-8 2,3-dichloroacrylonitrile 

Relevant articles and documents

CONDENSED DIAZEPINONES, THEIR COMPOSITIONS AND METHODS OF USE AS PHARMACEUTICALS

Disclosed are novel condensed diazepinones of formula I STR1 wherein B is a fused ring selected from STR2 X is--CH--or, when B is ortho-phenylene, X can also be nitrogen; A 1 is C 1-C. sub.2 alkylene; A 2 is C 1-C 2 when it is in the 2-position relative to the saturated heterocyclic ring nitrogen or a single bond or methylene when it is in the 3-or 4-position; R 1 is C 1-C 3 alkyl; R 2 is C. sub.1-C 7 alkyl, optionally hydroxy-substituted on at least one of its second to seventh carbon, or C 3-C 7 cycloalkyl, optionally hydroxy substituted, or C 3-C 7 cycloalkylmethyl; or R 1 and R 2 can, together with the nitrogen therebetween, be a 4-to 7-membered saturated monocyclic, heterocyclic ring which can optionally include an oxygen or N--CH 3 ; R 3 is hydrogen, chlorine, or methyl; R 4 is hydrogen or C 1-C 4 alkyl, R 5 is hydrogen, chlorine or C 1-C 4 alkyl; and Z is a single bond, oxygen, methylene or 1,2-ethylene; and NR 1 R 2--N oxides and nontoxic, pharmaceutically acceptable addition salts thereof. Also disclosed are pyrrolobenzodiazepinone intermediates, pharmaceutical compositions containing the condensed diazepinones and methods of using them to treat cardiovascular disorders, particularly bradycardia and bradyarrhythmia.