813433-68-0

Basic information

• Product Name: tert-butyl 2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate
• Synonyms: 2-pyrrolidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, methyl ester; tert-Butyl 2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate
• CAS NO: 813433-68-0
• Molecular Formula: C₁₂H₂₁NO₄
• Molecular Weight: 243.2994
• Mol File: 813433-68-0.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 304.797°C at 760 mmHg
• Flash Point: 138.137°C
• Density: 1.084g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.469
• PKA: -2.51±0.40(Predicted)
• CAS DataBase Reference: tert-butyl 2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate(813433-68-0)
• EPA Substance Registry System: tert-butyl 2-(2-methoxy-2-oxoethyl)pyrrolidine-1-carboxylate(813433-68-0)

Safety Data

• Hazardous Substances Data: 813433-68-0(Hazardous Substances Data)

Upstream product

• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 
• 186581-53-3 diazomethane 
• 67-56-1 methanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1202039-15-3 methyl (2'R,αR)-2-[N(1')-(α-methylbenzyl)pyrrolidin-2'-yl]ethanoate 
• 56879-46-0 2-(pyrrolidin-2-yl)acetic acid 
• 194154-91-1 (+/-)-1-(tert-Butoxycarbonyl)pyrrolidine-2-acetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 15761-39-4 N-tert-butoxycarbonyl-proline 
• 101555-60-6 2-(R)-carboxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 344-25-2 D-Prolin 
• 152665-79-7 (R)-tert-butyl 2-(2-diazoacetyl)pyrrolidine-1-carboxylate 
• 37784-17-1 N-(tert-butoxycarbonyl)-D-proline 
• 543-27-1 isobutyl chloroformate 

Downstream Products

• 1338968-17-4 C₂₉H₄₁NO₃ 
• 1178977-16-6 (S)-1,1-bis(4-propylphenyl)-2-(pyrrolidin-2-yl)ethanol 
• 1338968-19-6 C₃₃H₄₉NO₃ 
• 1178977-17-7 (S)-1,1-bis(4-pentylphenyl)-2-(pyrrolidin-2-yl)ethanol 
• 1338968-20-9 C₂₇H₂₅F₁₂NO₃ 
• 1178977-14-4 (S)-1,1-bis(3,5-bis(trifluoromethyl)phenyl)-2-(pyrrolidin-2-yl)ethanol 
• 1338968-12-9 C₂₃H₂₉NO₃ 
• 1178977-12-2 (S)-1,1-bis(4-methylphenyl)-2-(pyrrolidin-2-yl)ethanol 
• 340040-67-7 methyl 2-[(2R)-pyrrolidin-2-yl]acetate hydrochloride 

Relevant articles and documents

Tetrahydropyrido [3, 4-d] pyrimidine derivative and medical application thereof

The invention relates to a compound as shown in a general formula (I) or a stereoisomer, a deuterated compound, a solvate, a prodrug, a metabolite, a pharmaceutically acceptable salt or eutectic crystal thereof, an intermediate and a preparation method thereof, and application of the compound in preparation of drugs for treating diseases related to KRas-G12C activity or expression quantity.

USE OF AMINOINDANE COMPOUNDS IN TREATING OVERACTIVE BLADDER AND INTERSTITIAL CYSTITIS

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Aminoindane Compounds and Use Thereof in Treating Pain

The present application provides novel aminoindane compounds and methods for preparing and using these compounds. These compounds are useful in treating pain and/or itch in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) or (II) and a TRPV 1 receptor activator. In one embodiment, the TRPV 1 receptor activator is lidocaine.