81380-11-2

Upstream product

• 59005-41-3 (2R,3S)-4-Benzyloxy-3-methyl-butane-1,2-diol 
• 98-59-9 p-toluenesulfonyl chloride 
• 57280-24-7 (R)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-propan-1-ol 
• 100-39-0 benzyl bromide 

Downstream Products

• 81380-07-6 (2S,3R,6S)-1-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-heptan-3-ol 
• 81380-07-6 (2R,3S,6S)-1-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-heptan-3-ol 
• 80109-44-0 (2S,3R,6S)-1-Benzyloxy-2-methyl-6-(R)-oxiranyl-heptan-3-ol 
• 81380-09-8 [(2S,3R,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-3-methyl-tetrahydro-pyran-2-yl]-methanol 
• 78433-56-4 (R)-2-((R)-2-Benzyloxy-1-methyl-ethyl)-oxirane 

Relevant academic research and scientific papers

Studies toward polyether antibiotics: stereospecific synthesis of polysubstituted tetrhydropyrans

A stereospecific and general method for the preparartion of trans-tetrahydropyrans 1 and cis-tetrahydropyrans 2 from acyclic precursors are described.Compound 12, a possible intermediate for the synthesis of antibiotic X-14547A, has been synthesized.