81403-28-3Relevant academic research and scientific papers
Synthesis of ethyl and phenyl amido(ethoxyphenylalaninyl)phosphate compounds
Jalalifar,Javidan,Khalikov
experimental part, p. 1097 - 1100 (2012/10/07)
The synthetic route for preparation of three phosphoramides containing amino acid and their precursors in good yield and mild conditions is reported. This involved the synthesis of the ethyl and phenyl phosphorodichloridate and its reaction with bis(β-chloroethyl) amine or diethylamine, followed by the reaction of the products with phenyl alanine ethyl ester hydrochloride. In all the three compounds, because of the presence of chiral centre, the final products were obtained as a mixture of two diastereoisomers, which can be determined using 31P NMR and TLC methods. The structures of all the prepared compounds were confirmed by 1H NMR, 31P NMR, 13C NMR spectroscopy.
PHOSPHORYLATION COMPETITIVE DE DERIVES D'UREES/THIOUREES ET DE CARBAMATES/THIOCARBAMATES EN RELATION AVEC LE MODELE O-PHOSPHOBIOTINE.
Etemad-Moghadam, G.,Klaebe, A.,Perie, J. J.
, p. 61 - 74 (2007/10/02)
The phosphorylation of a number of heterocyclic substrates, such as ureas and carbamates, and their sulfur analogues, has been investigated with the object of clarifying previous results concerning the site of phosphorylation of this type of substrate, wh
