81568-76-5

Upstream product

• 95-51-2 o-chloroaniline 
• 100-47-0 benzonitrile 
• 58058-40-5 N-(2-chloro-phenyl)-benzamidine 
• 108-94-1 cyclohexanone 
• 528-29-0 1,2-Dinitrobenzene 
• 74864-94-1 N₁-(2-chlorophenyl)benzene-1,2-diamine 
• 98-88-4 benzoyl chloride 
• 74002-26-9 N-(2-chlorophenyl)-N-(2-nitrophenyl)amine 

Downstream Products

• 2622-67-5 1,2-diphenyl-1H-benzoimidazole 
• 201-71-8 benzimidazo<1,2-f>phenanthridine 

Relevant academic research and scientific papers

Transition-Metal-Free Synthesis of 1,2-diphenyl-1H-benzo[d] Imidazole Derivatives from N-phenylbenzimidamides and Cyclohexanones

A transition-metal-free strategy for the formation of 1,2-diphenyl-1H-benzo[d] imidazoles from N-phenylbenzimidamides and cyclohexanones is introduced. This is the first report on the direct synthesis of 1,2-diphenyl-1H-benzo[d] imidazoles from cyclohexanones and N-phenylbenzimidamides via iodine- promoted oxidative cyclization. Non-aromatic cyclohexanones were smoothly dehydrogenated, and acted as an aryl source using oxygen as a green oxidant. The catalytic use of iodine makes this method quite simple, more economical and convenient. Under optimized conditions, various substituted 1,2-diphenyl-1H-benzo[d] imidazoles were smoothly reacted, and the desired substituted imidazoles were generated with moderate to excellent yields. (Figure presented.).

Electrochemical Reactions. Part 24. Reductive Cyclisation of i-(2-Halogenophenyl)-j-phenyl Compounds: A General Reaction

The phenyl ?-radical formed by reduction of aryl halides in an aprotic solvent undergoes efficient radical substitution on an adjacent benzene ring.Several examples of this cyclisation reaction are given.The reaction is appropriate for the synthesis of 6-membered aromatic rings where the two reacting phenyl groups are held in a cis-configuration by an olefin bond or another aromatic ring.