82419-33-8

Basic information

• Product Name: 7,8-DIFLUORO-2,3-DIHYDRO-3-METHYL-4H-BENZOXAZINE
• Synonyms: 7,8-DIFLUORO-2,3-DIHYDRO-3-METHYL-4H-BENZOXAZINE;7,8 DIFLURO-2,3-DIHYDRO-3-METHYL-4H-BENZOXAZINE;7,8-difluoro-3-Methyl-3,4-dihydro-2H-1,4-benzoxazine;7,8-DIFLUORO-3-METHYL-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZINE
• CAS NO: 82419-33-8
• Molecular Formula: C₉H₉F₂NO
• Molecular Weight: 185.1706664
• Product Categories: sulfonyl compound
• Mol File: 82419-33-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 240.267 °C at 760 mmHg
• Flash Point: 99.11 °C
• Appearance: /
• Density: 1.22 g/cm³
• Vapor Pressure: 0.038mmHg at 25°C
• Refractive Index: 1.485
• CAS DataBase Reference: 7,8-DIFLUORO-2,3-DIHYDRO-3-METHYL-4H-BENZOXAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7,8-DIFLUORO-2,3-DIHYDRO-3-METHYL-4H-BENZOXAZINE(82419-33-8)
• EPA Substance Registry System: 7,8-DIFLUORO-2,3-DIHYDRO-3-METHYL-4H-BENZOXAZINE(82419-33-8)

Safety Data

• Hazardous Substances Data: 82419-33-8(Hazardous Substances Data)

Usage

General Description

7,8-Difluoro-2,3-dihydro-3-methyl-4H-benzoxazine is an organic compound with the molecular formula C9H8F2NO. It is a benzoxazine derivative, which is a class of heterocyclic compounds containing a benzene ring fused to an oxazine ring. This chemical is used in the synthesis of various pharmaceuticals and as a building block in organic chemistry. It has potential applications in the development of new drugs and materials. The presence of fluorine atoms in its structure may confer unique properties that make it useful in specific chemical reactions or biological activities.

InChI:InChI=1/C9H9F2NO/c1-5-4-13-9-7(12-5)3-2-6(10)8(9)11/h2-3,5,12H,4H2,1H3

Upstream product

• 112136-69-3 (R)-(+)-7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine 
• 77-92-9 citric acid 
• 117321-74-1 7,8-difluoro-3-methyl-2H-1,4-benzoxazine 
• 82419-26-9 2,3-difluoro-6-nitrophenol 
• 771-69-7 2,3,4-trifluoronitrobenzene 
• 82419-32-7 3,4-difluoro-2-(2-oxopropyloxy)nitrobenzene 

Downstream Products

• 106939-42-8 (S)-7,8-difluoro-3,4-dihydro-3-methyl-2H-1,4-benzoxazine 
• 112136-69-3 (R)-(+)-7,8-difluoro-3,4-dihydro-3-methyl-2H-[1,4]benzoxazine 
• 1129-46-0 (R)-(+)-2-phenoxypropionic acid 
• 86794-25-4 9-(4-Benzyl-piperazin-1-yl)-8-fluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid 

Relevant articles and documents

Palladium Supported on Carbon Nanoglobules as a Promising Catalyst for Selective Hydrogenation of Nitroarenes

The catalysts 1?wt% palladium supported on carbon nanoglobules (CNGs) were shown to be highly active in the liquid-phase hydrogenation of various nitroarenes and provided nearly 100% selectivity to aromatic amines at complete conversion under mild conditions (323?K, 0.5?MPa, 1?h). The catalytic activity (in terms of turnover frequency and substrate conversion) and selectivity depend on the kind of CNGs support, catalyst preparation method and the reaction conditions (solvent nature). The Pd/CNGs catalyst can be repeatedly used while maintaining the same catalytic performance. The excellent performances of Pd/CNGs catalysts can be due to the globular morphology of the supports as well as the absence of micropores and pronounced surface defects. Graphic Abstract: [Figure not available: see fulltext.]

Synthesizing method of novel ofloxacin intermediate

The invention relates to the field of medicine synthesizing, in particular to a synthesizing method of a novel ofloxacin intermediate as shown in structural formula (II). The synthesizing method includes: allowing 2,3,4-trifluoro nitrobenzene to have reac

A new convenient method for the synthesis of 2H-1,4-benzoxazine derivatives from nitroketones via intramolecular reductive cyclization

Potentially bioactive 2H-1,4-benzoxazine derivatives could be conveniently prepared in one step from the corresponding nitroketones using 10% palladium on carbon with triethylamine in the presence of hydrogen (Pd/C-TEA-H2) system. Several other