100311-75-9Relevant academic research and scientific papers
Total Synthesis of Leukotriene B44> and Homo-LTB4 from D-Mannitol
Merrer, Yves Le,Gravier-Pelletier, Christine,Micas-Languin, Dominique,Mestre, Francoise,Dureault, Annie,Depezay, Jean-Claude
, p. 2409 - 2416 (2007/10/02)
A convergent total synthesis of leukotriene B4 and its homo analogue has been carried out via enantiomerically pure α-hydroxy aldehydes, chiral key intermediates obtained from D-mannitol and connected at a four carbon atom interval by Wittig re
A Chemoenzymatic Synthesis of Leukotriene B4
Han, Chao-Qi,DiTullio, Dennis,Wang, Yi-Fong,Sih, Charles J.
, p. 1253 - 1258 (2007/10/02)
A total synthesis of leukotriene B4 (1) is accomplished by the assembly of the key chirons 2 and 3, which are prepared via enzymatic methods.
SIMPLE EFFICIENT SYNTHESIS OF LTB4 AND 12-epi-LTB4
Zamboni, Robert,Rokach, Joshua
, p. 2631 - 2634 (2007/10/02)
Using L- and D-arabinose respectively as the source of chirality at C-12 in LTB4, efficient new syntheses of LTB4 and 12-epi-LTB4 have been realized.
