82573-53-3

Basic information

• Product Name: Benzamide, N-(1-methyl-1-phenylethyl)-
• CAS NO: 82573-53-3
• Molecular Formula: C16H17NO
• Molecular Weight: 239.317
• Mol File: 82573-53-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(1-methyl-1-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(1-methyl-1-phenylethyl)-(82573-53-3)
• EPA Substance Registry System: Benzamide, N-(1-methyl-1-phenylethyl)-(82573-53-3)

Safety Data

• Hazardous Substances Data: 82573-53-3(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 585-32-0 2-phenyl-2-propylamine 
• 55-21-0 benzamide 
• 98-83-9 isopropenylbenzene 
• 300561-20-0 N-benzoyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamide 
• 32366-26-0 cumyl azide 
• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 3575-19-7 2-bromo-2-phenylpropane 
• 93-97-0 benzoic acid anhydride 
• 826-54-0 2-methyl-2-phenyl-propanamide 
• 98-82-8 Isopropylbenzene 
• 582-61-6 benzoyl azide 

Downstream Products

• 249764-80-5 C₁₇H₁₉NOS 
• 249764-82-7 2-iodo-N-(2-phenyl-2-propyl)benzamide 
• 249764-77-0 C₁₇H₁₇NO₂ 
• 249764-72-5 N-(2-phenylpropan-2-yl)-2-(trimethylsilyl)benzamide 
• 249764-70-3 3-hydroxy-2-(1-methyl-1-phenylethyl)-2,3-dihydro-1H-isoindol-1-one 
• 1252815-44-3 C₁₉H₂₁NO 
• 1252815-45-4 2-hydroxy-N-cumylbenzamide 
• 1252815-46-5 2-fluoro-N-cumylbenzamide 
• 1252815-42-1 2-(2'-hydroxypropyl)-N-cumylbenzamide 
• 90-16-4 1,2,3-benzotriazin-4(3H)-one 
• 25465-49-0 N³-allylbenzotriazinone 
• 86863-90-3 2-(trimethylsilyl)benzonitrile 
• 17876-72-1 2-(trimethylsilyl)benzamide 
• 54705-16-7 2-methylsulfanyl-benzamide 

Relevant articles and documents

Synthesis of Benzoisoselenazolones via Rh(III)-Catalyzed Direct Annulative Selenation by Using Elemental Selenium

Isoselenazolone derivatives have attracted significant research interest because of their potent therapeutic activities and indispensable applications in organic synthesis. Efficient construction of functionalized isoselenazolone scaffolds is still challenging, and thus new synthetic approaches with improved operational simplicity have been of particular interest. In this manuscript, we introduce a rhodium-catalyzed direct selenium annulation by using stable and tractable elemental selenium. A series of benzamides as well as acrylamides were successfully coupled with selenium under mild reaction conditions, and the obtained isoselenazolones could be pivotal synthetic precursors for several organoselenium compounds. Based on the designed control experiments and X-ray absorption spectroscopy measurements, we propose an unprecedented selenation mechanism involving a highly electrophilic Se(IV) species as the reactive selenium donor. The reaction mechanism was further verified by a computational study.

Ortho-directed functionalization of arenes using magnesate bases

Ortho-directed functionalisation of arenes using lithium alkylmagnesate bases were achieved, demonstrating the potential use of arylmagnesates as suitable arylanions, without a further transmetallation step, for challenging functionalizations such as fluorination, hydroxylation, arylation, vinylation and alkylation through epoxide ring-opening.

Studies on development of sufficiently chemoselective N-acylation reagents: N-Acyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamides

A variety of storable N-acyl-N-(2,3,4,5,6-pentafluorophenyl)methanesulfonamides (4a-e) prepared from N-2,3,4,5,6-pentafluorophenylmethanesulfonamide (3), have been developed after systematic research on the structure-reactivity relationship and were found to serve as N-acylation reagents exhibiting sufficiently good chemoselectivity. (C) 2000 Elsevier Science Ltd.