83-10-3

Usage

Uses

Used in Pharmaceutical Industry:
Antipyrinecarboxylic acid is used as an analgesic and antipyretic agent for the treatment of fever and pain. Its similar properties to antipyrine make it a potential alternative for managing these conditions.
Used in Anti-inflammatory Applications:
Antipyrinecarboxylic acid is used as an anti-inflammatory agent for treating conditions such as rheumatoid arthritis. Its potential anti-inflammatory properties may help alleviate symptoms and reduce inflammation associated with these disorders.
Used in Antioxidant Therapy:
Antipyrinecarboxylic acid is used as an antioxidant agent for treating oxidative stress-related disorders. Its potential antioxidant properties may help protect cells from damage caused by reactive oxygen species and support overall health.
Used in Research and Development:
Antipyrinecarboxylic acid is used as a subject of research to further explore its therapeutic potential, safety profile, and possible applications in various medical conditions. Ongoing studies aim to better understand its mechanisms of action and optimize its use in clinical settings.

InChI:InChI=1/C12H12N2O3/c1-8-10(12(16)17)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,1-2H3,(H,16,17)

Upstream product

• 75-44-5 phosgene 
• 60-80-0 antipyrine 
• 71-43-2 benzene 
• 950-81-2 4-formyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one 
• 10013-09-9 1-phenyl-2,3-dimethyl-4-hydroxymethyl-pyrazoline-5-on 
• 6538-52-9 (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-glyoxylic acid 
• 144481-38-9 1,5-dimethyl-2-phenyl-4-trichloroacetyl-1,2-dihydro-pyrazol-3-one 
• 132624-53-4 4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-thiocarbonyl)-morpholine 
• 40570-67-0 4-acetyl-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one 
• 108875-23-6 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid dimethylamide 
• 66379-85-9 1,5-dimethyl-2-phenyl-4-(2,2,2-trichloro-1-hydroxy-ethyl)-1,2-dihydro-pyrazol-3-one 
• 107056-79-1 (1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-glyoxylic acid ethyl ester 

Downstream Products

• 5426-65-3 4-bromoantipyrine 
• 873413-12-8 bis-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-ketone 
• 60-80-0 antipyrine 
• 1140-38-1 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4?carboxylic acid 
• 61226-16-2 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid 4-(5-methyl-isoxazol-3-ylsulfamoyl)-anilide 
• 61226-21-9 Antipyrinsaeurechlorid 
• 1197040-29-1 phenyl isocyanate 
• 188047-58-7 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4?carbonyl chloride 
• 95307-16-7 2-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carbonyl)-amino]-4-methylsulfanyl-butyric acid 
• 95307-11-2 2-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carbonyl)-amino]-4-methylsulfanyl-butyric acid ethyl ester 
• 95307-14-5 2-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carbonyl)-amino]-pentanedioic acid 
• 95307-13-4 2-[(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carbonyl)-amino]-pentanedioic acid diethyl ester 
• 95305-50-3 C₂₈H₃₂N₆O₄S₂ 
• 1251-85-0 diantipyrinylmethane 

Relevant academic research and scientific papers

Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives

Deregulation of c-Met receptor tyrosine kinase activity leads to tumorigenesis and metastasis in animal models. More importantly, the identification of activating mutations in c-Met, as well as MET gene amplification in human cancers, points to c-Met as a

HETEROCYCLIC COMPOUND AS PROTEIN KINASE INHIBITOR

Provided are novel heterocyclic compounds useful as anti-cancer drugs by suppressing protein kinase activities of growth factor receptors such as c-Met, pharmaceutical compositions containing the same, and methods for using the compound.

AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET

The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.