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83-10-3

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83-10-3 Usage

Description

Antipyrinecarboxylic acid, also known as 4-hydroxyantipyrine or 4-hydroxyphenazone, is a chemical compound derived from antipyrine, a medication used for treating fever and pain. It is a metabolite of antipyrine, formed in the liver during its metabolism, and is excreted in the urine. Antipyrinecarboxylic acid possesses analgesic, antipyretic, anti-inflammatory, and antioxidant properties, making it a potential candidate for treating conditions such as rheumatoid arthritis and oxidative stress-related disorders. However, further research is required to fully understand its therapeutic potential and safety profile.

Uses

Used in Pharmaceutical Industry:
Antipyrinecarboxylic acid is used as an analgesic and antipyretic agent for the treatment of fever and pain. Its similar properties to antipyrine make it a potential alternative for managing these conditions.
Used in Anti-inflammatory Applications:
Antipyrinecarboxylic acid is used as an anti-inflammatory agent for treating conditions such as rheumatoid arthritis. Its potential anti-inflammatory properties may help alleviate symptoms and reduce inflammation associated with these disorders.
Used in Antioxidant Therapy:
Antipyrinecarboxylic acid is used as an antioxidant agent for treating oxidative stress-related disorders. Its potential antioxidant properties may help protect cells from damage caused by reactive oxygen species and support overall health.
Used in Research and Development:
Antipyrinecarboxylic acid is used as a subject of research to further explore its therapeutic potential, safety profile, and possible applications in various medical conditions. Ongoing studies aim to better understand its mechanisms of action and optimize its use in clinical settings.

Check Digit Verification of cas no

The CAS Registry Mumber 83-10-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 83-10:
(4*8)+(3*3)+(2*1)+(1*0)=43
43 % 10 = 3
So 83-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H12N2O3/c1-8-10(12(16)17)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,1-2H3,(H,16,17)

83-10-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid

1.2 Other means of identification

Product number -
Other names 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83-10-3 SDS

83-10-3Relevant articles and documents

Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives

Norman, Mark H.,Liu, Longbin,Lee, Matthew,Xi, Ning,Fellows, Ingrid,D'Angelo, Noel D.,Dominguez, Celia,Rex, Karen,Bellon, Steven F.,Kim, Tae-Seong,Dussault, Isabelle

experimental part, p. 1858 - 1867 (2012/05/05)

Deregulation of c-Met receptor tyrosine kinase activity leads to tumorigenesis and metastasis in animal models. More importantly, the identification of activating mutations in c-Met, as well as MET gene amplification in human cancers, points to c-Met as a

AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET

-

Page/Page column 18, (2010/02/17)

The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.

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