83247-14-7Relevant academic research and scientific papers
Palladium-Catalyzed Reactions of Terminal Acetylenes and Olefins with Halo-1,3-azoles
Sakamoto, Takao,Nagata, Hideo,Kondo, Yoshinori,Shiraiwa, Masafumi,Yamanaka, Hiroshi
, p. 823 - 828 (2007/10/02)
The palladium-catalyzed reactions of 4-bromo- and 5-bromothiazoles, as well as 4-bromo and 5-bromooxazoles with terminal acetylenes gave ethynyl derivatives in 43-89percent yields, whereas the reactions of 2-bromothiazoles and iodo-N-methylimidazoles affo
Heterocycles from Phosphonium Salts: A Facile Method for Modification of the 4(5)-Methyl Group of Thiazoles
Webb, R. Lee,Lam, Bing L.,Lewis, Joseph J.,Wellman, George R.
, p. 639 - 640 (2007/10/02)
Thiazolyl phosphonium salts, formed from the condensation of acyl vinyl phosphonium salts with thioamides and thiourea, are readily functionalized in high yield.The sequence represents a useful general synthesis of multifunctional thiazoles.
