83375-20-6

Basic information

• Product Name: 2,4-dimethoxy-6-(methoxycarbonylmethyl)benzoic acid
• Synonyms: 2,4-dimethoxy-6-(methoxycarbonylmethyl)benzoic acid
• CAS NO: 83375-20-6
• Molecular Weight: 254.24
• Mol File: 83375-20-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2,4-dimethoxy-6-(methoxycarbonylmethyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dimethoxy-6-(methoxycarbonylmethyl)benzoic acid(83375-20-6)
• EPA Substance Registry System: 2,4-dimethoxy-6-(methoxycarbonylmethyl)benzoic acid(83375-20-6)

Safety Data

• Hazardous Substances Data: 83375-20-6(Hazardous Substances Data)

Upstream product

• 6110-30-1 methyl <3,5-dihydroxy-2-(methoxycarbonyl)phenyl>acetate 
• 877-88-3 3,5-dimethoxybenzyl bromide 
• 4670-10-4 (3,5-dimethoxyphenyl)acetic acid 
• 6512-26-1 methyl 2,4-dimethoxy-6-(methoxycarbonylmethyl)benzoate 
• 100118-53-4 methyl 2-hydroxy-4-methoxy-6-(methoxycarbonylmethyl)benzoate 
• 602278-05-7 (2-formyl-3,5-dimethoxy-phenyl)-acetic acid methyl ester 
• 3686-57-5 2,4-dimethoxy-6-methylbenzoic acid 
• 616-38-6 carbonic acid dimethyl ester 
• 67-56-1 methanol 
• 4778-99-8 2-carboxymethyl-4,6-dimethoxy-benzoic acid 
• 6512-32-9 methyl 2-(3,5-dimethoxyphenyl)acetate 

Downstream Products

• 83375-23-9 2,4-Dimethoxy-6-(7-methoxy-5-methyl-4-oxo-4H-chromen-2-ylmethyl)-benzoic acid 
• 4778-99-8 2-carboxymethyl-4,6-dimethoxy-benzoic acid 
• 6803-02-7 6-methoxymellein 
• 19314-92-2 3,4-dihydro-6,8-dihydroxy-3-methylisochromen-1-one 
• 924300-55-0 3-(4-hydroxy-3,5-dimethyl-phenyl)-6,8-dimethoxy-isochromen-1-one 
• 1044871-80-8 3-(3,5-dimethyl-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-6,8-dimethoxyisoquinolin-1(2H)-one 
• 1044872-19-6 3-[3,5-dimethyl-4-(2-(4-methyl piperazin-1-yl)-ethoxy)-phenyl]-6,8-dimethoxy-isochromen-1-one 
• 924300-54-9 acetic acid 4-(6,8-dimethoxy-1-oxo-1H-isochromen-3-yl)-2,6-dimethyl-phenyl ester 
• 924300-53-8 acetic acid 4-(6,8-dimethoxy-1,3-dioxo-isochroman-4-carbonyl)-2,6-dimethyl-phenyl ester 
• 924300-56-1 3-[4-(2-chloro-ethoxy)-3,5-dimethyl-phenyl]-6,8-dimethoxy-isochromen-1-one 
• 924300-57-2 3-[3,5-dimethyl-4-(2-morpholin-4-yl-ethoxy)-phenyl]-6,8-dimethoxy-isochromen-1-one 

Relevant articles and documents

TREATMENT OF DISEASES BY EPIGENETIC REGULATION

The present disclosure provides non-naturally occurring polyphenol compounds that inhibit the bromodomain and extra terminal domain (BET) proteins. The disclosed compositions and methods can be used for treatment and prevention of cancer, including NUT midline carcinoma, Burkitt's Lymphoma, Acute Myelogenous Leukemia, and Multiple Myeloma; autoimmune or inflammatory diseases or conditions, and sepsis.

PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF COMPLEX DISEASES AND THEIR DELIVERY BY INSERTABLE MEDICAL DEVICES

The present invention relates to polyphenol-like compounds that are useful for inhibiting VCAM-1 expression, MCP-1 expression and/or SMC proliferation in a mammal. The disclosed compounds are useful for regulating markers of inflammatory conditions, including vascular inflammation, and for treatment and prevention of inflammatory and cardiovascular diseases and related disease states.

An efficient synthesis of 3,5-dimethoxyhomophthalic acid, a key intermediate for synthesis of natural isocoumarins

3,5-Dimethoxyhomophthalic acid was prepared efficiently in three steps, from 3,5-dimethoxybenzyl bromide via rhodium-catalyzed direct carbonylation to 3,5-dimethoxyphenylacetic acid followed by successive o-formylation and oxidation. Isocoumarins related