83817-43-0Relevant articles and documents
The preparation, characterization and catalytic activity of Ni NPs supported on porous alginate-g-poly(p-styrene sulfonamide-co-acrylamide)
Alavinia, Sedigheh,Ghorbani-Vaghei, Ramin
, p. 29728 - 29740 (2021/10/06)
Herein, we report the synthesis of nickel nanoparticles under mild conditions using porous alginate-g-poly(p-styrene sulfonamide-co-acrylamide) as a protecting/stabilizing agent and sodium borohydride as a reducing agent. The porous cross-linked polymeric support was preparedviacombining the use of sol-gel, nanocasting, and crosslinking techniques, in which thep-styrene sulfonamide monomer (PSSA) andN,N′-methylene-bis (acrylamide) (MBA) cross-linker underwent copolymerization on the surface of sodium alginate in the presence of a SiO2nanoparticle (NP) template (Alg-PSSA-co-ACA). The prepared catalyst (Alg-PSSA-co-ACA@Ni) showed high catalytic activity for the one-step synthesis of 1,3,4-oxadiazoles from the reaction of hydrazides and aryl iodides through isocyanide insertion/cyclization.
A pharmaceutical intermediate the body is wicked oxadiazole compound synthesis method (by machine translation)
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Paragraph 0046; 0047; 0048; 0049; 0050; 0051; 0064-0098, (2017/08/25)
The present invention provides a following formula (I) of the oxadiazole compound shows wickedly synthetic method, said method comprising: in the organic solvent, the catalyst organic copper compound, in the presence of alkali and activator, a compound of formula (II) compound of formula (III) in the reaction in an inert atmosphere, thus formula (I) compounds, wherein R1 And R2 Are each independently H, C1 - C6 Alkyl, C1 - C6 Alkoxy, halogen or nitro; X is halogen. The method through the catalyst, alkali, organic solvent activator and the appropriate selection/combined, but to a high yield of the objective product, in the medical intermediate synthesis field and has a wide application and great industrial. (by machine translation)
Iron(III)/TEMPO-Catalyzed Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazoles by Oxidative Cyclization under Mild Conditions
Zhang, Guofu,Yu, Yidong,Zhao, Yiyong,Xie, Xiaoqiang,Ding, Chengrong
, p. 1373 - 1377 (2017/06/27)
A simple and efficient cationic Fe(III)/TEMPO-catalyzed oxidative cyclization of aroyl hydrazones has been developed for the synthesis of 2,5-disubstituted 1,3,4-oxadiazole derivatives. The reaction offers a broad scope, good functional-group tolerance, and high yields under mild conditions in the presence of O 2.