83852-28-2Relevant articles and documents
Copper(ii) complexes of macrocyclic and open-chain pseudopeptidic ligands: synthesis, characterization and interaction with dicarboxylates
Faggi, Enrico,Gavara, Raquel,Bolte, Michael,Fajarí, Lluís,Juliá, Luís,Rodríguez, Laura,Alfonso, Ignacio
, p. 12700 - 12710 (2015)
Mono- and dinuclear Cu(ii) complexes were prepared with pseudopeptidic open chain and macrocyclic ligands, respectively. They were characterized by UV-vis spectroscopy, EPR, HRMS and X-ray diffraction. The Cu(ii) cation is coordinated by two amines and tw
A configuration can control the synthesis of 2 - (4 - nitro) butyryl pyridine nitrogen - oxidation method of the (by machine translation)
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Paragraph 0064, (2017/08/31)
The invention relates to a configuration can control the synthesis of 2 - (4 - nitro) butyryl pyridine nitrogen - oxygen compounds of the method, comprises the following steps: 1) will be 2 - ene acyl pyridine nitrogen - arrive compound and nitromethane o
Efficient macrocyclization of U-turn preorganized peptidomimetics: The role of intramolecular H-bond and solvophobic effects
Becerril, Jorge,Bolte, Michael,Burguete, M. Isabel,Galindo, Francisco,Garcia-Espana, Enrique,Luis, Santiago V.,Miravet, Juan F.
, p. 6677 - 6686 (2007/10/03)
Simple peptidomimetic molecules derived from amino acids were reacted with meta- and parabis(bromomethyl) benzene in acetonitrile to very efficiently yield macrocyclic structures. The cyclization reaction does not require high dilution techniques and seems to be insensitive to the size of the formed macrocycle. The analysis of data obtained by 1H NMR, single-crystal X-ray diffraction, fluorescence measurements, and molecular mechanics indicate that folded conformations can preorganize the system for an efficient cyclization. The role played by intramolecular hydrogen-bonding and solvophobic effects in the presence of folded conformations is analyzed.