83896-44-0

Basic information

• Product Name: 18α-Glycylrrhizin
• Synonyms: [(18α)-20β-Carboxy-11-oxo-30-norolean-12-en-3β-yl]2-O-β-D-glucopyranuronosyl-α-D-glucopyranosiduronic acid;18α-Glycylrrhizin;18α-Glycyrrhizin;18α-Glycyrrhizinic acid
• CAS NO: 83896-44-0
• Molecular Formula: C₄₂H₆₂O₁₆
• Molecular Weight: 822.93208
• Mol File: 83896-44-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 971.4°C at 760 mmHg
• Flash Point: 288.1°C
• Appearance: /
• Density: 1.43g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 18α-Glycylrrhizin(CAS DataBase Reference)
• NIST Chemistry Reference: 18α-Glycylrrhizin(83896-44-0)
• EPA Substance Registry System: 18α-Glycylrrhizin(83896-44-0)

Safety Data

• Hazardous Substances Data: 83896-44-0(Hazardous Substances Data)

Usage

Uses

18α-Glycyrrhizic Acid is a derivative of Glycyrrhizic Acid (G735150), a triterpene saponin used in the traditional Chinese medicinal preparation for its anti-inflammatory , antiulcerous and antiallergic effects.

InChI:InChI=1/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21+,22+,23+,24+,25+,26+,27-,28+,29+,30-,31-,34+,35+,38-,39+,40+,41-,42-/m1/s1

Upstream product

• 118325-23-8 C₆₈H₉₄O₃₀ 
• 118342-92-0 C₅₄H₇₆O₂₁ 
• 118325-22-7 licorice-saponin A₃ 
• 42294-03-1 β-Glycyrrhicic acid tripotassium salt 
• 42294-03-1 β-Glycyrrhicic acid monopotassium salt 
• 68340-31-8 2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl-11-oxoolean-12-en-30-oate 

Downstream Products

• 137734-07-7 1-O-<(3β,20β)-11,30-Dioxo-30-desoxy-30-(N-L-phenylalanine methyl ester)olean-12-en-3-yl>-2-O-<β-D-6-oxo-6-desoxy-6-(N-L-phenylalanine methyl ester)glucopyranosyl>-α-D-6-oxo-6-desoxy-6-(N-L-phenylalanine methyl ester)glucopyranoside 
• 1416780-06-7 C₆₁H₈₅NO₁₉ 
• 1416780-00-1 C₅₁H₇₃NO₁₇ 
• 1416779-99-1 C₅₁H₇₃NO₁₆ 
• 1416780-05-6 C₆₀H₈₉NO₁₉ 
• 1416779-91-3 C₄₉H₇₁NO₁₄ 
• 1416779-90-2 C₄₈H₇₅NO₁₄ 
• 1416779-84-4 C₅₆H₇₈N₂O₁₃ 
• 1416780-15-8 C₆₃H₈₇NO₂₂ 
• 1416780-14-7 C₆₃H₈₇NO₂₁ 
• 135503-68-3 6',6''-dibenzyl-30-stearyl glycyrrhizin 
• 87919-12-8 hydroxysuccinimidyl N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylate 
• 87919-08-2 benzyl N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylate 
• 87919-07-1 benzyl N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-ε-aminohexanoate 

Relevant articles and documents

METHOD FOR PRODUCING GLYCYRRHIZINIC ACID AND GALACTURO GLYCYRRHIZINIC ACID, AND INTERMEDIATE USED FOR THE PRODUCTION METHOD

PROBLEM TO BE SOLVED: To provide a synthesis method that makes it possible to produce high-purity glycyrrhizinic acid or galacturo glycyrrhizinic acid, simply and in high yields. SOLUTION: A production method includes performing glycosylation of position-3 hydroxy group of glycyrrhetinic acid, then performing selective galactosylation or glycosylation at position-2', and through deprotection, performing selective oxidation of a primary hydroxy group. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Licorice-saponins A3, B2, C2, D3, and E2, five new oleanene-type triterpene oligoglycosides from Chinese glycyrrhizae radix

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