83948-28-1

Basic information

• Product Name: N-(trimethylsilyl)cinnamaldimine
• Synonyms: N-(trimethylsilyl)cinnamaldimine
• CAS NO: 83948-28-1
• Molecular Weight: 203.359
• Mol File: 83948-28-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: N-(trimethylsilyl)cinnamaldimine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(trimethylsilyl)cinnamaldimine(83948-28-1)
• EPA Substance Registry System: N-(trimethylsilyl)cinnamaldimine(83948-28-1)

Safety Data

• Hazardous Substances Data: 83948-28-1(Hazardous Substances Data)

Upstream product

• 104-55-2 3-phenyl-propenal 
• 4039-32-1 lithium hexamethyldisilazane 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 14371-10-9 (E)-3-phenylpropenal 
• 13436-03-8 bis(trimethylsilyl)diazene 

Downstream Products

• 83948-42-9 3,3-Dimethyl-4-(β-styryl)-2-azetidinone 
• 1885-38-7 cinnamic nitrile 
• 135299-43-3 5-chloro-8-chloromethyl-3,3-dimethyl-6-phenyl-7-thianonanam 
• 135299-42-2 8-chloro-3,3-dimethyl-5-(α-chlorobenzyl)-6-thianonanam 
• 135299-41-1 1-Allyl-3,3-dimethyl-4-((E)-styryl)-azetidin-2-one 
• 96735-61-4 (S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-((E)-styryl)-azetidin-2-one 
• 96735-59-0 (S)-3-((R)-1-Hydroxy-ethyl)-4-((E)-styryl)-azetidin-2-one 
• 96735-60-3 Formic acid (R)-1-[(S)-2-oxo-4-((E)-styryl)-azetidin-3-yl]-ethyl ester 
• 83948-39-4 (E)-3-Amino-1-phenyl-1,5-hexadiene 
• 137105-66-9 (3S,4aS,6R)-3-Methyl-6-phenyl-4,4a,5,6-tetrahydro-3H-pyrido[1,2-c][1,3]oxazin-1-one 
• 96735-59-0 (S)-3-((S)-1-Hydroxy-ethyl)-4-((E)-styryl)-azetidin-2-one 
• 96735-59-0 (3S,4S)-3-((S)-1-Hydroxy-ethyl)-4-((E)-styryl)-azetidin-2-one 

Relevant articles and documents

Lithium perchlorate mediated three component reaction for the preparation of primary amines

In the presence of lithium perchlorate in diethyl ether, LPDE, a three- component reaction between aldehydes, sodium hexamethyldisilazane or lithium hexamethyldisilazane, LHMDS, and different nucleophiles proceeds smoothly to afford primary amines in good yields.

Access to nitriles from aldehydes mediated by an oxoammonium salt

A scalable, high yielding, rapid route to access an array of nitriles from aldehydes mediated by an oxoammonium salt (4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate) and hexamethyldisilazane (HMDS) as an ammonia surrogate has been developed. The reaction likely involves two distinct chemical transformations: reversible silyl-imine formation between HMDS and an aldehyde, followed by oxidation mediated by the oxoammonium salt and desilylation to furnish a nitrile. The spent oxidant can be easily recovered and used to regenerate the oxoammonium salt oxidant.

Lithium perchlorate mediated three-component preparation of primaryaminoesters

A three-component reaction between an aldehyde, metallated hexamethyldisilazane and a functionalized organozinc compound proceeded smoothly in the presence of LiClO4 in diethyl ether to afford primary amino esters in good yields.