84197-47-7

Upstream product

• 5922-60-1 2-amino-5-chlorobenzonitrile 
• 98-88-4 benzoyl chloride 
• 1073-69-4 N-4-chlorophenylhydrazine 
• 41019-24-3 2-(4-chlorophenyl)-1-(1-phenylethylidene)hydrazine 
• 23746-76-1 5-chloro-2-phenylindole 
• 98-86-2 acetophenone 
• 108-86-1 bromobenzene 
• 13939-06-5 molybdenum hexacarbonyl 
• 23746-88-5 5-Chloro-2-phenyl-indol-3-one oxime 

Downstream Products

• 1251582-29-2 C₂₂H₁₅ClN₂O₂ 
• 1296129-01-5 C₂HF₃O₂*C₂₄H₂₃ClN₄O₃ 
• 1251582-31-6 C₂₅H₁₉ClN₂O₄ 
• 1251592-18-3 C₂₂H₂₁ClN₄O 
• 1227807-92-2 C₁₇H₁₃ClN₂ 

Relevant academic research and scientific papers

Synthesis of 2-Aminobenzonitriles through Nitrosation Reaction and Sequential Iron(III)-Catalyzed C-C Bond Cleavage of 2-Arylindoles

A variety of 2-aminobenzonitriles were prepared from 2-arylindoles in good to excellent yields through tert-butylnitrite (TBN)-mediated nitrosation and sequential iron(III)-catalyzed C-C Bond cleavage in a one-pot fashion. The 2-aminobenzonitriles can be used to rapidly synthesize benzoxazinones by intramolecular condensation. The present method features an inexpensive iron(III) catalyst, gram scalable preparations, and novel C-C bond cleavage of indoles.

Palladium-catalyzed carbonylative synthesis of N-(2-cyanoaryl)benzamides and sequential synthesis of quinazolinones

A convenient procedure for the synthesis of N-(2-cyanoaryl)benzamides has been developed. Using aryl bromides and 2-aminobenzonitriles as the substrates, Mo(CO)6 as the CO source, the desired amides were produced in good yields. Quinazolinones

INHIBITORS OF HIV REPLICATION

Compounds of formula (I): wherein R1, R2, A1, A2, A3, A4, X and Y are as defined herein, are useful as inhibitors of HIV replication.