849217-53-4

Basic information

• Product Name: Methanesulfonic acid, trifluoro-, 6-methoxy-7-(phenylmethoxy)-4-quinolinyl ester
• CAS NO: 849217-53-4
• Molecular Formula: C18H14F3NO5S
• Molecular Weight: 413.374
• Mol File: 849217-53-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Methanesulfonic acid, trifluoro-, 6-methoxy-7-(phenylmethoxy)-4-quinolinyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid, trifluoro-, 6-methoxy-7-(phenylmethoxy)-4-quinolinyl ester(849217-53-4)
• EPA Substance Registry System: Methanesulfonic acid, trifluoro-, 6-methoxy-7-(phenylmethoxy)-4-quinolinyl ester(849217-53-4)

Safety Data

• Hazardous Substances Data: 849217-53-4(Hazardous Substances Data)

Upstream product

• 75665-88-2 1-(4-(benzyloxy)-5-methoxy-2-nitrophenyl)ethanone 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 100-39-0 benzyl bromide 
• 1835-11-6 4-benzyloxy-3-methoxyacetophenone 
• 75665-73-5 1-(2-amino-4-(benzyloxy)-5-methoxyphenyl)ethanone 
• 205448-29-9 7-benzyloxy-4-hydroxy-6-methoxyquinoline 
• 421-83-0 trifluoromethane sulfonyl chloride 

Downstream Products

• 849217-50-1 N-[3-fluoro-4-[[7-hydroxy-6-methoxy-quinolin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 849217-52-3 N-(4-{[7-{[2-(diethylamino)ethyl]oxy}-6-(methyloxy)quinolin-4-yl]oxy}-3-fluorophenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 
• 849217-64-7 foretinib 
• 849217-51-2 N-[3-fluoro-4-[[7-benzyloxy-6-methoxy-quinolin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide 

Relevant articles and documents

C-MET MODULATORS AND METHODS OF USE

The present invention provides compounds, which have activity for modulating protein kinase enzymatic activity and are potentially useful for modulating cellular activities such as, e.g., proliferation, differentiation, programmed cell death, migration and chemoinvasion. The present invention also provides compositions containing such compounds, and methods for producing and using such compounds and compositions.