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849217-52-3

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849217-52-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 849217-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,2,1 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 849217-52:
(8*8)+(7*4)+(6*9)+(5*2)+(4*1)+(3*7)+(2*5)+(1*2)=193
193 % 10 = 3
So 849217-52-3 is a valid CAS Registry Number.

849217-52-3Downstream Products

849217-52-3Relevant articles and documents

C-MET MODULATORS AND METHODS OF USE

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, (2008/06/13)

The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate and/or modulate kinase receptor, particularly c-Met, KDR, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.

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