849937-89-9 Usage
Uses
Used in Medicinal Chemistry:
4,6-difluoro(pyridin-2-yl)carboxylic acid is used as a building block for the development of new pharmaceutical compounds. Its unique structure and functional groups can be utilized to create novel drug candidates with potential therapeutic applications.
Used in Organic Synthesis:
4,6-difluoro(pyridin-2-yl)carboxylic acid is used as a synthetic intermediate for the preparation of various organic compounds. Its distinctive properties, such as the presence of fluorine atoms and the carboxylic acid group, can be exploited in the synthesis of complex organic molecules for different industries.
Further research and experimentation are needed to fully understand and explore the properties and potential uses of 4,6-difluoro(pyridin-2-yl)carboxylic acid.
Check Digit Verification of cas no
The CAS Registry Mumber 849937-89-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,9,9,3 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 849937-89:
(8*8)+(7*4)+(6*9)+(5*9)+(4*3)+(3*7)+(2*8)+(1*9)=249
249 % 10 = 9
So 849937-89-9 is a valid CAS Registry Number.
849937-89-9Relevant articles and documents
Regiochemically flexible substitutions of di-, tri-, and tetrahalopyridines: The trialkylsilyl trick
Schlosser, Manfred,Bobbio, Carla,Rausis, Thierry
, p. 2494 - 2502 (2007/10/03)
(Chemical Equation Presented) 2,4-Difluoropyridine, 2,4-dichloropyridine, 2,4,6-trifluoropyridine, 2,4,6-trichloropyridine and 2,3,4,6-tetrafluoropyridine react with standard nucleophiles exclusively at the 4-position under halogen displacement. However, the regioselectivity can be completely reversed if a trialkylsilyl group is introduced in the 5-position of the 2,4-dihalopyridines or in the 3-position of the 2,4,6-trihalopyridines or 2,3,4,6-tetrahalopyridine. Then only the halogen most remote from the bulky silyl unit (at the 2-position in the case of the 2,4-halopyridines, at the 6-position with the other substrates) gets involved in the exchange process. After removal of the silyl protective group the nucleophile is invariably found to occupy the nitrogen-neighboring position.
