850723-16-9

Basic information

• Product Name: methanesulfonic acid 2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethyl ester
• Synonyms: methanesulfonic acid 2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethyl ester
• CAS NO: 850723-16-9
• Molecular Weight: 646.799
• Mol File: 850723-16-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methanesulfonic acid 2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: methanesulfonic acid 2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethyl ester(850723-16-9)
• EPA Substance Registry System: methanesulfonic acid 2-{2-[2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethyl ester(850723-16-9)

Safety Data

• Hazardous Substances Data: 850723-16-9(Hazardous Substances Data)

Upstream product

• 76-84-6 triphenylmethyl alcohol 
• 124-63-0 methanesulfonyl chloride 
• 745048-17-3 1,1,1-triphenyl-2,5,8,11,14,17,20-heptaoxadocosan-22-ol 
• 5617-32-3 heptaethylene glycol 
• 76-83-5 trityl chloride 
• 745048-16-2 19,19,19-triphenyl-3,6,9,12,15,18-hexaoxanonadec-1-ylmethanesulfonate 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 146462-59-1 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane 
• 133699-09-9 10,10,10-triphenyl-3,6,9-trioxadecan-1-ol 
• 127999-16-0 19-(triphenylmethyl)-1,4,7,10,13,16,19-heptaoxanonadecanol 

Downstream Products

• 1274892-60-2 2-{2-[2-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethanol 
• 745048-18-4 22-azido-1,1,1-triphenyl-2,5,8,11,14,17,20-heptaoxadocosane 

Relevant articles and documents

CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF

The disclosure relates to novel lipidic compounds, method of manufacturing lipid nanoparticles (LNPs) containing thereof, lipid nanoparticles (LNPs) containing thereof, and the use of the LNPs for the delivery of nucleic acid. The lipidic compounds as disclosed herein is a cleavable lipidic compound comprising at least one terminal radical of formula (I): Y-(CHR)n-Z-(CHR')p-Q * (I) wherein: - * is the end linked, directly or not, to one C10 to C55 lipophilic or hydrophobic tail-group; - Y is a radical selected in the group consisting of methyl, methoxy, trifluoromethyl, imidazolyl, or is one hydrogen; - Z is a radical -NH-CH2-CO-O-** or a radical -CR''(NH2)-CO-O-** with ** that is the end closest to Q and R'' that is selected in the group consisting of hydrogen, methyl radical and trifluoromethyl radical; - Q is a radical -NH-CH2-CO-O-*** or a radical -CR''(NH2)-CO-O-*** with R'' selected in the group consisting of hydrogen, methyl radical and trifluoromethyl radical and *** that is the end linked, directly or not, to said lipophilic or hydrophobic tail-group; - R et R' are, independently one from the other, one hydrogen, one methyl radical or one trifluoromethyl radical; - n et p are independently one from the other 0, 1 or 2; or one of its pharmaceutically acceptable salts and with said compound being in all the possible racemic, enantiomeric and diastereoisomeric isomer forms.