85302-11-0Relevant articles and documents
Synthesis of 4-aroyl-5-arylpyrazoles and 4-aroyl-3-arylpyrazoles via the reaction of enaminodiketones with substituted hydrazines
Choshi, Tominari,Hatae, Noriyuki,Hibino, Satoshi,Kotouge, Rika,Nishiyama, Takashi,Oikawa, Tsutomu,Ono, Kanako,Yamauchi, Akira
, p. 25 - 45 (2020/01/28)
Pyrazole is a five-membered heterocyclic compound and is one of the important heterocycles in the fields of medicine and pharmacology. Here, we demonstrate the reactivity of symmetrical enaminodiketones 8–14 with substituted hydrazines. When using alkylhy
Reaction of 2-Dimethylaminomethylene-1,3-diones with Dinucleophiles. I. Synthesis of 1,5-Disubstituted 4-Acylpyrazoles
Schenone, Pietro,Mosti, Luisa,Menozzi, Giulia
, p. 1355 - 1361 (2007/10/02)
Reaction of open-chain and cyclic sym-1,3-diones with N,N-dimethylformamide dimethyl acetal gave, generally in high yield, a series of sym-2-dimethylaminomethylene-1,3-diones which reacted with phenylhydrazine and methylhydrazine to afford, generally in satisfactory yield, a number of 1,5-disubstituted 4-acylpyrazoles.The applications and limits of this new pyrazole synthesis are presented and discussed.