854676-79-2

Upstream product

• 56961-35-4 4-(4-chloro-phenyl)-3-hydroxy-4-oxo-2-phenyl-butyric acid 
• 1260146-93-7 2-(4-chlorophenyl)-2-hydroxy-N-methoxy-N-methylacetamide 
• 1260146-94-8 C₁₆H₂₆ClNO₃Si 
• 66985-46-4 (+/-)-2-(4-chlorophenyl)-2-(trimethylsiloxy)-acetonitrile 
• 32174-34-8 methyl 4-chloromandelate 
• 104-88-1 4-chlorobenzaldehyde 
• 64-17-5 ethanol 

Downstream Products

• 1260146-56-2 1-hydroxy-1-(4-chlorophenyl)-3-phenylpropanone 
• 110220-78-5 2-(4-chloro-phenyl)-2-hydroxy-3-phenyl-propionic acid 
• 74-11-3 para-chlorobenzoic acid 

Relevant academic research and scientific papers

Enantioselective aerobic oxidation of α-hydroxy-ketones catalyzed by oxidovanadium(V) methoxides bearing chiral, N-salicylidene- tert -butylglycinates

Chiral oxidovanadium(V) methoxides prepared from 3,5-disubstituted-N- salicylidene-l-tert-butylglycines and vanadyl sulfate in air-saturated MeOH serve as highly enantioselective catalysts for asymmetric aerobic oxidations and kinetic resolution of alkyl, aryl, and heteroaryl α-hydroxy-ketones with differed α-substituents at ambient temperature in toluene or TBME (tert-butyl methyl ether). The best scenarios involve the use of complexes which bear the tridendate templates derived from 3,5-diphenyl- or 3-o-biphenyl-5-nitro-salicyaldehyde. The kinetic resolution selectivities of the aerobic oxidation process are in the range of 12 to >1000 based on the selectivity factors (krel).