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Usage

Uses

Used in Organic Synthesis:
5-Bromo-2-ethylaminopyridine is used as a building block for the synthesis of various organic compounds. Its unique structure allows for the formation of new chemical entities through reactions such as substitution, addition, and condensation. This makes it a valuable intermediate in the preparation of complex molecules.
Used in Pharmaceutical Research:
5-Bromo-2-ethylaminopyridine is used as a starting material or intermediate in the development of new pharmaceutical compounds. Its structural features can be exploited to design and synthesize potential drug candidates with desired biological activities. The presence of the bromine atom and ethylamine group can be utilized to introduce specific functional groups or to modify the chemical properties of the resulting molecules, which can lead to improved pharmacological properties.
Used in Chemical Research:
5-Bromo-2-ethylaminopyridine is used as a research tool in various chemical studies. Its reactivity and the ability to form different types of chemical bonds make it an interesting subject for investigation. Researchers can explore its properties, such as its electronic structure, reactivity, and stability, to gain insights into the behavior of similar compounds and to develop new synthetic strategies.
Used in Material Science:
5-Bromo-2-ethylaminopyridine can be used as a component in the development of new materials with specific properties. Its incorporation into polymers, for example, can lead to materials with altered electronic, optical, or mechanical properties. This can be particularly useful in the design of advanced materials for applications in electronics, photonics, or other high-tech industries.
Used in Analytical Chemistry:
5-Bromo-2-ethylaminopyridine can be used as a reagent or a reference compound in analytical chemistry. Its unique chemical properties can be exploited for the development of new analytical methods or for the calibration of analytical instruments. This can be particularly useful in the identification and quantification of related compounds in complex mixtures or in the study of reaction mechanisms.

Upstream product

• 1072-97-5 5-bromo-2-pyridylamine 
• 141-52-6 sodium ethanolate 
• 64-19-7 acetic acid 
• 7169-97-3 N-(5-bromopyridin-2-yl)acetamide 

Relevant academic research and scientific papers

NOVEL COMPOUNDS

The present invention relates to novel compounds of formula (I) and methods for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C-terminal hydrolase 30 or ubiquitin spec

Discovery of a Novel Series of 7-Azaindole Scaffold Derivatives as PI3K Inhibitors with Potent Activity

The phosphoinositide 3-kinase (PI3K) inhibitors potently inhibit the signaling pathway of PI3K/AKT/mTOR, which provides a promising new approach for the molecularly targeted cancer therapy. In this work, a novel series of 7-azaindole scaffold derivatives was discovered by the fragment-based growing strategy. The structure-activity relationship profiles identified that the 7-azaindole scaffold derivatives exhibit potent activity against PI3K at molecular and cellular levels as well as cell proliferation in a panel of human tumor cells.

PI3K inhibitor, preparation method and application thereof in pharmacy

The invention belongs to the technical field of pharmaceuticals and particularly relates to a PI3K inhibitor, a preparation method and application thereof in the pharmacy. The PI3K inhibitor is a compound of the structure shown by the general formula I or medically acceptable salt of the inhibitor. After the PI3K inhibitor is tested with a PI3K biochemical activity test method, the compound has excellent inhibitory activity to PI3K alpha and PI3K gamma, wherein the IC50 values of a plurality of compounds to the PI3K alpha and PI3K gamma reach nanomole grades (smaller than 100 nM). The result shows that the compounds can provide the inhibitor with better effectiveness and selectivity for curing PI3K-acted proliferative disease, and further a targeted drug for curing No. I type diabetes mellitus, lung disease, breast cancer, prostatic cancer, solid tumor, lymphoma, cardiovascular disease, rheumatoid arthritis, leukemia and the like can be hopefully developed. (Please see the general formula I in the description.).

Compounds that modulate PPAR activity and methods of preparation

This invention relates to compounds that alter PPAR activity. The invention also relates to pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing dyslipidemia, hypercholesterolemia, obesity, hyperglycemia, atherosclerosis, hypertriglyceridemia and hyperinsulinemia in a mammal. The present invention also relates to methods for making the disclosed compounds.