85810-81-7

Basic information

• Product Name: methyl acetyl of methyl phenylglyoxylate
• Synonyms: methyl acetyl of methyl phenylglyoxylate
• CAS NO: 85810-81-7
• Molecular Weight: 210.23
• Mol File: 85810-81-7.mol

Chemical Properties

• CAS DataBase Reference: methyl acetyl of methyl phenylglyoxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl acetyl of methyl phenylglyoxylate(85810-81-7)
• EPA Substance Registry System: methyl acetyl of methyl phenylglyoxylate(85810-81-7)

Safety Data

• Hazardous Substances Data: 85810-81-7(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 536-74-3 phenylacetylene 
• 67-66-3 chloroform 
• 10028-15-6 ozone 
• 611-73-4 Benzoylformic acid 
• 637-44-5 phenylpropyolic acid 
• 932-88-7 1-iodo-2-phenylethyne 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 149-73-5 trimethyl orthoformate 
• 124-41-4 sodium methylate 
• 83-13-6 diethyl 2-phenylmalonate 
• 932-87-6 1-Bromo-2-phenylacetylene 

Downstream Products

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 111047-52-0 methyl N-p-toluenesulfonyl-1-imino-1-phenylacetate 
• 553663-08-4 (4aR,6R,7R,8S,8aS)-6-Methoxy-7,8-bis-(4-methoxy-benzyloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-2-carbothioic acid S-[2-(2-iodo-phenyl)-ethyl] ester 
• 553663-03-9 Acetic acid (2S,4aR,6S,7R,8S,8aR)-7-acetoxy-2-[2-(2-iodo-phenyl)-ethylsulfanylcarbonyl]-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 553663-07-3 Acetic acid (4aR,6R,7R,8S,8aS)-7-acetoxy-2-[2-(2-iodo-phenyl)-ethylsulfanylcarbonyl]-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 553663-06-2 (4aR,6R,7R,8R,8aR)-7,8-Dihydroxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-2-carbothioic acid S-[2-(2-iodo-phenyl)-ethyl] ester 
• 553663-02-8 (4aR,6S,7R,8S,8aR)-6-Methoxy-2-phenyl-7,8-bis-trimethylsilanyloxy-hexahydro-pyrano[3,2-d][1,3]dioxine-2-carboxylic acid methyl ester 
• 51785-62-7 Benzoic acid (2R,3R,4S,5R,6S)-4,5-diacetoxy-6-methoxy-2-methyl-tetrahydro-pyran-3-yl ester 
• 150650-49-0 methyl 2,3-di-O-acetyl-4-O-benzoyl-6-deoxy-β-D-galactopyranoside 
• 733001-99-5 S-ethyl 2-O-benzyl-4,6-O-(α-methoxycarbonyl)benzylidene-3-O-(2-naphthalenylmethyl)-1-thio-α-D-mannopyranoside 
• 553663-05-1 (4aR,6R,7R,8S,8aS)-6-Methoxy-2-phenyl-7,8-bis-trimethylsilanyloxy-hexahydro-pyrano[3,2-d][1,3]dioxine-2-carboxylic acid methyl ester 
• 553663-01-7 (4aR,6S,7R,8R,8aS)-7,8-Dihydroxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-2-carboxylic acid methyl ester 

Relevant articles and documents

Highly enantioselective aza-henry reaction of ketimines catalyzed by a chiral bifunctional thiourea-tertiary amine derived from quinine

We have developed a highly enantioselective aza-Henry reaction of aryl α-ketoester-derived N-Ts ketimines with a wide range of substrate scope by a simpler bifunctional thiourea-tertiary amine catalyst derived from quinine. A variety of ketimines were investigated and corresponding products were obtained in excellent yields (up to 99% yield) with excellent enatioselectivities (up to 99% ee).

One-pot efficient synthesis of aryl α-keto esters from aryl-ketones

A novel one-pot synthesis of aryl α-keto esters was developed through oxidation of aryl-ketones using selenium dioxide, esterification accompanied by ketalization, and hydrolysis. Both aromatics and heteroaromatics gave good yields by this one-pot method.

Facile preparation of the methyl acetal of methyl phenylglyoxylate

The methyl acetal of methyl phenylglyoxylate has been prepared from halophenylethynes, N-iodosuccinimide and catalytic amounts of (hydroxy(p-tosyloxy)iodo)benzene or p-toluenesulfonic acid in methanol at room temperature.

Facile formations of ketals of α, α-dihaloacetophenones

Ketals of α,α-dihaloacetophenones are prepared in high yields from phenylethyne and N-halosuccinimide with catalytic quantities of p-toluenesulfonic acid.

Diphenylsilane Reduction of C=O and C=N Bearing Electron-Withdrawing Group in the Presence of Aluminium(III) Chloride

Several α-keto esters and methyl N-p-tolylsulfonyl-2-aryl-2-iminoacetates were reduced to the corresponding α-hydroxy esters and methyl N-p-tolylsulfonyl-2-arylglycinates in high yields by a combination of aluminium(III) chloride and diphenylsilane under operating conditions in which diphenylsilane was added to the pre-formed substrate-aluminium(III) chloride complex in dichloromethane and the mixture stirred.The case of an exactly equivalent amount of aluminium(III) chloride as the substrate resulted in good results.

Electrochemical Hydroxylation, Methoxylation, and Hydroxymethylation of Active Methine Compounds

Hydroxylation, methoxylation, or hydroxymethylation at the active methine group of phenylmalonate, benzylmalonate and diphenylacetate were achieved by anodic oxidation.

Oxidative Decarboxylation of Propiolic Acids

The combination of iodine and iodine pentoxide in methanol was used to convert phenylpropiolic acid and 2-hexynoic acid to the corresponding ketal esters of one less carbon.In both cases, iodoacetylenic compounds were shown to be intermediates.In the case of the phenylpropiolic acid, a diiodoalkene was isolated and shown to be a second intermediate.